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Reply to "Proactive Customized Protocol for Oral Management in Head and Neck Cancer Patients Planned for Radiotherapy".对“针对计划接受放疗的头颈癌患者的口腔管理主动定制方案”的回复
J Maxillofac Oral Surg. 2025 Jun;24(3):723-724. doi: 10.1007/s12663-025-02509-0. Epub 2025 Mar 20.

本文引用的文献

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Osteoradionecrosis of the mandible after radiotherapy for head and neck cancer: risk factors and dose-volume correlations.头颈部癌症放疗后下颌骨放射性骨坏死:危险因素和剂量-体积相关性。
Acta Oncol. 2019 Oct;58(10):1373-1377. doi: 10.1080/0284186X.2019.1643037. Epub 2019 Jul 31.
2
Incidence of, and risk factors for, mandibular osteoradionecrosis in patients with oral cavity and oropharynx cancers.口腔和口咽癌患者下颌骨放射性骨坏死的发生率及危险因素。
Oral Oncol. 2017 Sep;72:98-103. doi: 10.1016/j.oraloncology.2017.07.014. Epub 2017 Jul 16.
3
Cause and occurrence timing of osteoradionecrosis of the jaw: a retrospective study focusing on prophylactic tooth extraction.颌骨放射性骨坏死的病因及发生时间:一项聚焦于预防性拔牙的回顾性研究
Oral Maxillofac Surg. 2016 Dec;20(4):337-342. doi: 10.1007/s10006-016-0570-5. Epub 2016 Jul 11.
4
Osteoradionecrosis of the Jaws: Clinico-Therapeutic Management: A Literature Review and Update.颌骨放射性骨坏死:临床治疗管理:文献综述与更新
J Maxillofac Oral Surg. 2015 Dec;14(4):891-901. doi: 10.1007/s12663-015-0762-9. Epub 2015 Mar 10.
5
Longitudinal evaluation of health-related quality of life after osteoradionecrosis of the mandible.下颌骨放射性骨坏死术后健康相关生活质量的纵向评估。
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Osteoradionecrosis of the jaws: current understanding of its pathophysiology and treatment.颌骨放射性骨坏死:对其病理生理学和治疗的当前认识
Br J Oral Maxillofac Surg. 2008 Dec;46(8):653-60. doi: 10.1016/j.bjoms.2008.04.006. Epub 2008 Jun 17.
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Relationship between oral health status and development of osteoradionecrosis of the mandible: a retrospective longitudinal study.口腔健康状况与下颌骨放射性骨坏死发生之间的关系:一项回顾性纵向研究。
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Dental extractions and radiotherapy in head and neck oncology: review of the literature.口腔颌面-头颈部肿瘤的拔牙与放射治疗:文献综述
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9
Radiotherapy-induced mandibular bone complications.放射治疗引起的下颌骨并发症。
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Osteoradionecrosis of the jaws: clinical characteristics and relation to the field of irradiation.颌骨放射性骨坏死:临床特征及其与放射野的关系。
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针对计划接受放疗的头颈癌患者的口腔管理主动定制方案。

Proactive Customized Protocol for Oral Management in Head and Neck Cancer Patients Planned for Radiotherapy.

作者信息

Kenkere Deepika, Gudibande Manjunath Narasappa, Deepa C, Srinath K S, Harshitha K R, Reddy Mallika P

机构信息

Department of Dentistry, Fellow Oral Oncosurgery, Department of ENT and Head & Neck Surgery, Sri Devaraj Urs Medical College, Tamaka, Kolar India.

Department of Radiotherapy, Sri Devaraj Urs Medical College, Tamaka, Kolar India.

出版信息

J Maxillofac Oral Surg. 2024 Dec;23(6):1366-1370. doi: 10.1007/s12663-021-01511-6. Epub 2021 Jan 21.

DOI:10.1007/s12663-021-01511-6
PMID:39618433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11607274/
Abstract

Osteoradionecrosis (ORN) is a nemesis of radiotherapy which adversely affects the life of an individual. It is more often seen with conventional external beam radiotherapy using telecobalt machine. Newer radiotherapy techniques are being used in developed nations to circumvent its inherent disadvantages. A higher incidence of ORN is seen in dentate jaws because of extractions done for odontogenic infections in the post radiation period. Systematic evaluation of oral tissues and instituting appropriate therapeutic and prophylactic measures before, during and after completion of radiotherapy is mandatory. In our hospital since we use telecobalt radiotherapy it was deemed necessary to design our own protocol to reduce the incidence of this debilitating complication. Our protocol is based on recommended guidelines and which has been customized to our patient strata. We present the findings of a retrospective study on patients undergoing radiotherapy in whom this oral management protocol was used. This protocol has been effective in reducing the frequency of osteoradionecrosis at our tertiary care hospital.

摘要

放射性骨坏死(ORN)是放射治疗的一大难题,会对患者的生活产生不利影响。它在使用远距离钴治疗机进行的传统外照射放疗中更为常见。发达国家正在采用更新的放疗技术来规避其固有缺点。由于在放疗后阶段因牙源性感染而拔牙,ORN在有牙颌中的发生率更高。在放疗前、放疗期间和放疗完成后,对口腔组织进行系统评估并采取适当的治疗和预防措施是必不可少的。在我们医院,由于使用远距离钴放疗,因此认为有必要设计我们自己的方案以降低这种使人衰弱的并发症的发生率。我们的方案基于推荐指南,并已根据我们的患者群体进行了定制。我们展示了一项对接受放疗且使用了这种口腔管理方案的患者的回顾性研究结果。该方案在我们的三级护理医院有效降低了放射性骨坏死的发生率。