Lucamba Agnelo, Grillo Ricardo, Filipe Luzolo, Fernandes Maria Teresa
Department of Oral and Maxillofacial Surgery, Hospital Josina Machel, Luanda, Angola.
Oral and Maxillofacial Surgery Training Program, Foundation of Dentistry - Fundecto, University of São Paulo, São Paulo, Brazil.
J Maxillofac Oral Surg. 2024 Dec;23(6):1564-1568. doi: 10.1007/s12663-024-02302-5. Epub 2024 Aug 10.
Odontogenic infections, irrespective of regional economic conditions, are a global health concern. Some cases escalate to severe levels, complicating treatment, endangering lives, and reducing positive outcomes. Necrotizing fasciitis is particularly lethal, with purulent collections and infection-derived gases spreading to distant regions. Prompt surgical intervention is crucial, especially in patients with comorbidities like diabetes mellitus. This paper introduces a comprehensive treatment approach taken in Angola over the past 4 years. This protocol involves four key steps: combined antibiotic therapy (ceftriaxone, metronidazole, and aminoglycoside), prompt drainage with aggressive debridement, irrigation with sodium hypochlorite, and rapid removal of the infectious focus. This study reports its application in 13 patients over a 10-day period, demonstrating its efficacy in odontogenic necrotizing fasciitis. The protocol significantly reduced fatalities, and its success was acknowledged by the maxillofacial surgery department at Josina Machel Hospital. Challenges, such as a scarcity of maxillofacial surgeons, prompted innovative adaptations to treatment protocols. Although lacking statistical validation, the used protocol showcased effectiveness in treating odontogenic necrotizing fasciitis. Its emphasis on combined antibiotic therapy, aggressive surgical interventions, and specialized irrigation demonstrated notable success in reducing mortality rates.
无论地区经济状况如何,牙源性感染都是一个全球关注的健康问题。一些病例会升级到严重程度,使治疗复杂化,危及生命,并降低积极的治疗效果。坏死性筋膜炎尤其致命,脓性分泌物和感染产生的气体可扩散到远处。及时的手术干预至关重要,尤其是对于患有糖尿病等合并症的患者。本文介绍了安哥拉在过去4年中采取的综合治疗方法。该方案包括四个关键步骤:联合抗生素治疗(头孢曲松、甲硝唑和氨基糖苷类)、积极清创引流、用次氯酸钠冲洗以及迅速清除感染灶。本研究报告了该方案在10天内对13例患者的应用情况,证明了其在牙源性坏死性筋膜炎治疗中的有效性。该方案显著降低了死亡率,其成功得到了若西纳·马谢尔医院颌面外科的认可。诸如颌面外科医生短缺等挑战促使对治疗方案进行创新调整。尽管缺乏统计学验证,但所采用的方案在治疗牙源性坏死性筋膜炎方面显示出有效性。其对联合抗生素治疗、积极手术干预和专门冲洗的强调在降低死亡率方面取得了显著成功。