Mohammed Sohaib K, Budamagunta Sanjana, Khan Waleed A, Khan Muneeb, Lippmann Steven
Internal Medicine, Countess of Chester Hospital NHS Foundation Trust, Chester, GBR.
General Medicine, Deccan College of Medical Sciences, Hyderabad, IND.
Cureus. 2024 Oct 31;16(10):e72778. doi: 10.7759/cureus.72778. eCollection 2024 Oct.
Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn's disease. A relapsing, immune-modulated illness, it causes inflammation of the small and large intestines. UC is sometimes associated with extra-intestinal manifestations, including autoimmune cytopenias. Immune thrombocytopenic purpura (ITP) is a rare disorder which may induce an antibody-mediated, isolated reduction in platelet counts. ITP can present with extra-intestinal manifestations; the diagnosis follows the exclusion of other etiologies. Co-occurrences of ITP and UC in patients commonly are at the onset of UC or during illness recurrences. The severity of ITP correlates with the degree of UC pathology. We present a unique case of a 70-year-old presenting ulcerative colitis with immune thrombocytopenic purpura.
炎症性肠病（IBD）包括溃疡性结肠炎（UC）和克罗恩病。这是一种复发性、免疫调节性疾病，可导致小肠和大肠发炎。UC有时与肠外表现有关，包括自身免疫性血细胞减少症。免疫性血小板减少性紫癜（ITP）是一种罕见疾病，可导致抗体介导的血小板计数单独减少。ITP可伴有肠外表现；诊断需排除其他病因。患者中ITP和UC的共现通常发生在UC发病时或疾病复发期间。ITP的严重程度与UC病理程度相关。我们报告一例70岁患者同时出现溃疡性结肠炎和免疫性血小板减少性紫癜的独特病例。
