Dao Kevin T, Ashrafi Arian, Palmbach Matthew, Eftekhari Tanya, Fallahtafti Erfan, Nast Cynthia C, Eppanapally Sabitha
Internal Medicine, University of California, Los Angeles (UCLA)Kern Medical, Bakersfield, USA.
Internal Medicine, University of California, Los Angeles (UCLA) Kern Medical, Bakersfield, USA.
Cureus. 2024 Oct 30;16(10):e72736. doi: 10.7759/cureus.72736. eCollection 2024 Oct.
Fibrillary glomerulonephritis is a rare glomerular disease with some correlations between this condition alongside viral infections, malignancy, and autoimmune pathologies. However, the question regarding the pathogenesis is whether patients who develop fibrillary glomerulonephritis do so irrespective of these other pathologies or whether such pathologies induce fibrillary glomerulonephritis through an unknown mechanism. As such, attempts have been made to create associations with this disease to demonstrate further understanding. Here, we would like to present a very rare case of a patient with Hashimoto's thyroiditis associated with fibrillary glomerulonephritis and how such a diagnosis was made. Although autoimmune associations have been made alongside fibrillary glomerulonephritis, this case demonstrates one of the first cases of a patient with fibrillary glomerulonephritis and Hashimoto's thyroiditis. A discussion regarding the treatment and management of our patient, as well as the pathogenesis of this disease, will also be included.
纤维性肾小球肾炎是一种罕见的肾小球疾病，这种疾病与病毒感染、恶性肿瘤和自身免疫性疾病之间存在一定关联。然而，关于其发病机制的问题是，发生纤维性肾小球肾炎的患者是否独立于这些其他疾病而发病，或者这些疾病是否通过未知机制诱发纤维性肾小球肾炎。因此，人们试图建立与这种疾病的关联以加深理解。在此，我们想介绍一例非常罕见的病例，该患者患有与纤维性肾小球肾炎相关的桥本甲状腺炎，以及这种诊断是如何做出的。尽管纤维性肾小球肾炎已与自身免疫性疾病建立了关联，但该病例是纤维性肾小球肾炎合并桥本甲状腺炎的首批病例之一。本文还将讨论我们这位患者的治疗和管理，以及这种疾病的发病机制。
