斯里兰卡人桥本甲状腺炎概况：桥本甲状腺炎患者并发其他疾病的风险是否增加？
Profile of Hashimoto's Thyroiditis in Sri Lankans: Is There an Increased Risk of Ancillary Pathologies in Hashimoto's Thyroiditis?
作者信息
Siriweera Eranga Himalee, Ratnatunga Neelakanthi Vajira Illangakoon
机构信息
Department of Pathology, Faculty of Medicine, University of Peradeniya, Peradeniya 20400, Sri Lanka.
出版信息
J Thyroid Res. 2010 Oct 10;2010:124264. doi: 10.4061/2010/124264.
Abstract
Hashimoto's thyroiditis has been reported to be associated with many neoplastic and nonneoplastic thyroid pathologies. This retrospective study aims to determine the demographic profile of Hashimoto's thyroiditis in Sri Lankans, document ancillary pathologies in Hashimoto's thyroiditis, and determine whether there is an increased risk of occurrence of malignancies, benign neoplasms, and nonneoplastic benign lesions in Hashimoto's thyroiditis by comparing with thyroids showing multinodular goiters, follicular adenomas, and colloid nodules. The mean age of Hashimoto's thyroiditis is 43.3 years with the majority in the 41 to 60 year age group and a female to male ratio of 10.3 : 1. This study revealed a statistically significant increase of thyroid malignancies in association with Hashimoto's thyroiditis. The association of Papillary carcinoma, Non-Hodgkin's lymphoma, and Hurthle cell adenoma with Hashimoto's thyroiditis was statistically significant.
摘要
据报道，桥本甲状腺炎与许多肿瘤性和非肿瘤性甲状腺病变有关。这项回顾性研究旨在确定斯里兰卡人中桥本甲状腺炎的人口统计学特征，记录桥本甲状腺炎的附属病变，并通过与表现为结节性甲状腺肿、滤泡性腺瘤和胶样结节的甲状腺进行比较，确定桥本甲状腺炎患者发生恶性肿瘤、良性肿瘤和非肿瘤性良性病变的风险是否增加。桥本甲状腺炎患者的平均年龄为43.3岁，大多数在41至60岁年龄组，男女比例为10.3∶1。这项研究显示，与桥本甲状腺炎相关的甲状腺恶性肿瘤在统计学上有显著增加。乳头状癌、非霍奇金淋巴瘤和许特耳细胞腺瘤与桥本甲状腺炎的关联在统计学上具有显著性。
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