Liu Jiahui, Yang Junfeng, Fan Yu, Jiang Changchun
Department of Neurology, Baotou Central Hospital, Baotou, China.
Front Neurol. 2024 Nov 14;15:1359786. doi: 10.3389/fneur.2024.1359786. eCollection 2024.
This study examined the etiology, treatment response, and prognosis of patients with cerebral venous sinus thrombosis (CVST) at a single institution.
This retrospective study included patients diagnosed with CVST between January 2016 and December 2020 at Baotou Central Hospital. The data were collected from patient charts, including sex, age, comorbidities, pregnancy, smoking, alcohol drinking, symptoms at onset, radiological location, examinations, Glasgow coma scale (GCS) at admission, National Institutes of Health stroke scale (NIHSS) at admission, modified Rankin scale (mRS) at admission, and treatments.
The study included 31 patients (13 males and 18 females) aged 39.0 (interquartile range, 30.0-53.0) years. Three (9.7%) patients had a history of hypertension, one (3.2%) had a history of stroke, four (12.9%) had thrombotic disorders, six (19.4%) were pregnant (including three who delivered), four (12.9%) were smoking, and four (12.9%) were drinking alcohol. The GCS at admission was 15.0 (IQR, 15.0-15.0), the NIHSS at admission was 0.0 (IQR, 0.0-2.0), and the mRS at admission was 0.0 (IQR, 0.0-0.0). The patients were grouped according to their mRS (>0 vs. 0); there were no significant differences between the two groups regarding the patient characteristics (all > 0.05). Only an NIHSS of >0 at follow-up was associated with a 3-month mRS >0 ( < 0.001).
The median age of the patients with CVST was 39 years. The majority were female (58%), 13% had thrombotic disorders, and 19% were or were recently pregnant. Only a NIHSS of >0 at follow-up was associated with a 3-month mRS >0.
本研究在单一机构中对脑静脉窦血栓形成（CVST）患者的病因、治疗反应及预后进行了研究。
这项回顾性研究纳入了2016年1月至2020年12月在包头市中心医院被诊断为CVST的患者。数据从患者病历中收集，包括性别、年龄、合并症、妊娠情况、吸烟、饮酒、发病时症状、放射学定位、检查、入院时格拉斯哥昏迷量表（GCS）评分、入院时美国国立卫生研究院卒中量表（NIHSS）评分、入院时改良Rankin量表（mRS）评分以及治疗情况。
该研究纳入了31例患者（13例男性和18例女性），年龄为39.0（四分位数间距，30.0 - 53.0）岁。3例（9.7%）患者有高血压病史，1例（3.2%）有卒中病史，4例（12.9%）有血栓形成性疾病，6例（19.4%）为孕妇（包括3例已分娩者），4例（12.9%）吸烟，4例（12.9%）饮酒。入院时GCS评分为15.0（四分位数间距，15.0 - 15.0），入院时NIHSS评分为0.0（四分位数间距，0.0 - 2.0），入院时mRS评分为0.0（四分位数间距，0.0 - 0.0）。患者根据mRS评分（>0 vs. 0）进行分组；两组在患者特征方面无显著差异（均>0.05）。仅随访时NIHSS评分>0与3个月时mRS评分>0相关（<0.001）。
CVST患者的中位年龄为39岁。大多数为女性（58%），13%有血栓形成性疾病，19%为孕妇或近期分娩过。仅随访时NIHSS评分>0与3个月时mRS评分>0相关。
