Ibrahim Etedal Ahmed A, Hassan Mohamed Rofiedah Eisa, Hussien Mohamed Ahmed Khabab Abbasher, Haroun Mazin S, Abdalla Yassin Abdelrahim, Abdalla Omer Mohammed Eltahier, Mahmmoud Fadelallah Eljack Mohammed
Al-Neelain University, Faculty of Medicine, Khartoum, Sudan.
The National Center for Neurological Sciences, Khartoum, Sudan.
Ann Med Surg (Lond). 2022 Nov 17;84:104891. doi: 10.1016/j.amsu.2022.104891. eCollection 2022 Dec.
Cerebral venous sinus thrombosis (CVST) is a relatively uncommon cause of stroke that mainly affects young ladies, with a wide spectrum of symptoms severity, and prognosis. In this study, we aim to study the clinical profile and Risk Factors of CVST among Sudanese patients in Khartoum state hospitals.
This was a multi-center cross-sectional hospital-based study that covered 37 participants in three major hospitals in Khartoum, with radiologically confirmed Cerebral Venous Sinus Thrombosis (CVST).
About 37 patients were included in this study. The median age was 35 years; the range was 52 years, with a minimum age of 23 years and a maximum of 75 years. The commonest presenting feature was headache (n = 35; 94.6%), followed by blurring of vision (n = 25; 67.6%), while seizures is a presenting symptom in nearly half of the patients (n = 17; 45.9%), on examination papilledema was present in 83.8%. In this study 13.8% were pregnant, 31.0% were postpartum and OCPS users account for 27%. Regarding the involved sinus; Sagittal Venous Sinus and the transverse sinus were the most affected sinuses. Regarding treatment options: "low molecular weight heparin followed with warfarin" was found in 81.1%, followed by heparin in only 10.8%, while the new agents NOACs comprised only 8.1%.
Cerebral Venous Sinus Thrombosis is mainly a disease of child-bearing women, although significant proportions of men were affected. Cerebral Venous Sinus Thrombosis presents in a wide variety of signs and symptoms.
脑静脉窦血栓形成（CVST）是一种相对不常见的中风病因，主要影响年轻女性，症状严重程度和预后范围广泛。在本研究中，我们旨在研究喀土穆州立医院苏丹患者中CVST的临床特征和危险因素。
这是一项基于医院的多中心横断面研究，涵盖了喀土穆三家主要医院的37名参与者，经放射学确诊为脑静脉窦血栓形成（CVST）。
本研究纳入了约37例患者。中位年龄为35岁；年龄范围为52岁，最小年龄为23岁，最大年龄为75岁。最常见的表现特征是头痛（n = 35；94.6%），其次是视力模糊（n = 25；67.6%），而近一半的患者（n = 17；45.9%）有癫痫发作作为表现症状，检查时83.8%存在视乳头水肿。在本研究中，13.8%为孕妇，31.0%为产后，口服避孕药使用者占27%。关于受累静脉窦；矢状窦和横窦是受影响最严重的静脉窦。关于治疗方案：81.1%采用“低分子量肝素继以华法林”，仅10.8%采用肝素，而新型药物非维生素K拮抗剂（NOACs）仅占8.1%。
脑静脉窦血栓形成主要是育龄妇女的疾病，尽管有相当比例的男性受到影响。脑静脉窦血栓形成有各种各样的体征和症状。
