Bhatt Vaidehi D, Bhatt Kalpana D, Bhatt Deepak C, Dabir Supriya, Berendschot Tos T J M, Erckens Roel J, Webers Carroll A B
UBM Institute, Mumbai, India.
Department of Retina, Rajan Eye Care Pvt Ltd, Chennai, India.
Clin Ophthalmol. 2024 Nov 25;18:3441-3448. doi: 10.2147/OPTH.S494556. eCollection 2024.
Ocular cysticercosis, caused by larvae, presents significant public health challenges, especially in regions with poor sanitation. Traditional imaging techniques often fail to detect anterior segment cysticercosis accurately, necessitating the exploration of more advanced diagnostic modalities like Ultrasound Biomicroscopy (UBM).
A retrospective observational analysis was conducted on 18 eyes from 14 patients with cysticercosis involving the anterior segment. UBM imaging was performed using a Sonomed VuMax HD ultrasound biomicroscopy machine with a 50 MHz probe.
In the study, 18 eyes from 18 patients were analyzed, revealing 12 cases of conjunctival cysticercosis, 4 of anterior chamber cysticercosis, and 2 of iris cysticercosis. Patients averaged 37.89 (± 16.2) years, with a male predominance. Conjunctival cysts appeared as clear masses, occasionally eliciting inflammatory reactions. Iris involvement caused thinning near the angle, while anterior chamber cysts could displace the lens, leading to iris bombe in some instances.
UBM emerges as a valuable diagnostic tool for anterior segment cysticercosis, providing detailed imaging superior to traditional methods. Its cost-effectiveness and accessibility make it particularly valuable, especially in resource-constrained settings. Future research should focus on validating UBM's diagnostic accuracy and exploring its role in monitoring disease progression and treatment response.
由幼虫引起的眼囊尾蚴病带来了重大的公共卫生挑战,尤其是在卫生条件差的地区。传统成像技术常常无法准确检测眼前节囊尾蚴病,因此需要探索更先进的诊断方法,如超声生物显微镜检查(UBM)。
对14例患有眼前节囊尾蚴病患者的18只眼进行回顾性观察分析。使用配备50MHz探头的Sonomed VuMax HD超声生物显微镜进行UBM成像。
在该研究中,对18例患者的18只眼进行了分析,发现结膜囊尾蚴病12例,前房囊尾蚴病4例,虹膜囊尾蚴病2例。患者平均年龄为37.89(±16.2)岁,以男性为主。结膜囊肿表现为透明肿物,偶尔引发炎症反应。虹膜受累导致房角附近变薄,而前房囊肿可使晶状体移位,在某些情况下导致虹膜膨隆。
UBM成为眼前节囊尾蚴病的一种有价值的诊断工具,提供优于传统方法的详细成像。其成本效益和可及性使其特别有价值,尤其是在资源有限的环境中。未来的研究应侧重于验证UBM的诊断准确性,并探索其在监测疾病进展和治疗反应中的作用。