Srbely Victoria, Jeewa Aamir, Pidborochynski Tara, Lemaire-Paquette Samuel, Khoury Michael, Cunningham Chentel, Dhillon Santokh, Laroussi Nassiba Alami, Vaujois Laurence, Dallaire Frederic, Schantz Daryl, Armstrong Kathryn, Mawad Wadi, Bradley Timothy, Conway Jennifer
School of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Department of Pediatrics, Division of Cardiology, the Hospital for Sick Children, Toronto, Ontario, Canada.
CJC Pediatr Congenit Heart Dis. 2024 Jul 8;3(5):183-190. doi: 10.1016/j.cjcpc.2024.06.002. eCollection 2024 Oct.
Paediatric hypertrophic cardiomyopathy (HCM) is associated with sudden cardiac death, often resulting in restriction of strenuous physical activity. High levels of inactivity and a rise in youth obesity may increase risk of poor cardiovascular (CV) health in these patients. We aim to compare the CV disease risk profile of paediatric patients with HCM to Canadian youth.
Patients with HCM (10-19 years) were recruited from 10 paediatric cardiac centres in Canada. The CV disease risk profile was determined using the Healthy Hearts School Program questionnaire and Cardiovascular Health in Ambulatory Care Research Team (CANHEART) health index. Poisson regressions were used to assess associations between the CV disease risk profile of paediatric patients with HCM and the overall CANHEART health score.
A total of 56 subjects were enrolled (71% male, median age: 15.5 years [interquartile range: 13.8-16.8], median body mass index: 23.3 [interquartile range: 19.5-27.7]). Results of the CANHEART health index revealed that 89% of participants with HCM never tried smoking, 52% had a healthy body mass index, 39% consumed ≥5 fruits/vegetables per day, and 50% engaged in ≥60 minutes of walking or 20 minutes of running/jogging per day. When CANHEART intermediate and poor health index scores were combined, similar proportions were obtained for each group (HCM 82.1% vs Canadian youth 83.4%; = 0.724).
Many paediatric patients with HCM in Canada have intermediate or poor CV health as determined by the CANHEART health score, with high rates of obesity and low physical activity levels driving these trends. Interventions should be developed to promote positive CV health behaviours among patients with HCM.
小儿肥厚型心肌病（HCM）与心源性猝死相关，常导致剧烈体育活动受限。高水平的不活动和青少年肥胖率上升可能增加这些患者心血管（CV）健康不良的风险。我们旨在比较小儿HCM患者与加拿大青少年的心血管疾病风险状况。
从加拿大10个儿科心脏中心招募10 - 19岁的HCM患者。使用健康心脏学校项目问卷和门诊护理研究团队心血管健康（CANHEART）健康指数确定心血管疾病风险状况。采用泊松回归评估小儿HCM患者的心血管疾病风险状况与CANHEART总体健康评分之间的关联。
共纳入56名受试者（71%为男性，中位年龄：15.5岁[四分位间距：13.8 - 16.8]，中位体重指数：23.3[四分位间距：19.5 - 27.7]）。CANHEART健康指数结果显示，89%的HCM参与者从未尝试吸烟，52%的人具有健康的体重指数，39%的人每天食用≥5份水果/蔬菜，50%的人每天进行≥60分钟的步行或20分钟的跑步/慢跑。当将CANHEART中等和较差健康指数评分合并时，每组获得的比例相似（HCM为82.1%，加拿大青少年为83.4%；P = 0.724）。
根据CANHEART健康评分，加拿大许多小儿HCM患者的心血管健康处于中等或较差水平，肥胖率高和身体活动水平低推动了这些趋势。应制定干预措施，以促进HCM患者形成积极的心血管健康行为。
