Shan Jinyi, Cao Ziyi, Yu Siming
School of Graduate Studies, Heilongjiang University of Chinese Medicine, Harbin, People's Republic of China.
The First Clinical Medical College of Shaanxi, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi Province, People's Republic of China.
Int J Gen Med. 2024 Nov 27;17:5593-5609. doi: 10.2147/IJGM.S490049. eCollection 2024.
Diabetic kidney disease (DKD) is a form of kidney damage resulting from diabetes and represents a common, severe complication of the disease. Globally, DKD is a leading cause of chronic kidney disease (CKD). DKD occurs in both type 1 and type 2 diabetes patients, with early clinical manifestations including microalbuminuria and hypertension. As the condition progresses, symptoms such as massive proteinuria, hypoalbuminemia, and severe edema may appear. The key to treating DKD lies in controlling blood glucose and blood pressure, reducing proteinuria, and slowing the deterioration of kidney function. Acupuncture, a traditional Chinese medicine treatment, has shown some therapeutic effects on DKD through mechanisms such as regulating blood glucose, improving renal blood flow and microcirculation, antioxidation and anti-inflammation, and modulating gut microbiota.
糖尿病肾病（DKD）是由糖尿病导致的一种肾脏损害形式，是该疾病常见且严重的并发症。在全球范围内，DKD是慢性肾脏病（CKD）的主要病因。1型和2型糖尿病患者均可发生DKD，其早期临床表现包括微量白蛋白尿和高血压。随着病情进展，可能会出现大量蛋白尿、低白蛋白血症和严重水肿等症状。治疗DKD的关键在于控制血糖和血压、减少蛋白尿以及减缓肾功能恶化。针灸作为一种中医疗法，已通过调节血糖、改善肾血流和微循环、抗氧化和抗炎以及调节肠道微生物群等机制，对DKD显示出一定的治疗效果。
