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针刺改善新冠后面部水肿:一份符合 CARE 标准的病例报告。

Facial edema after covid-19 ameliorated by acupuncture: A CARE-compliant case report.

作者信息

Han Yike, He Shiqiao, Keeler Crystal Lynn, Yin Hongwu, Chen Lifang

机构信息

The Third School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.

Innovations to Wellness, Oakland, CA.

出版信息

Medicine (Baltimore). 2025 Jul 18;104(29):e43407. doi: 10.1097/MD.0000000000043407.

DOI:10.1097/MD.0000000000043407
PMID:40696628
Abstract

RATIONALE

Covid-19-induced inflammation and edema of the facial skin is a new problem, albeit still somewhat uncommon. To date, there are no published reports on the use of acupuncture for treating facial edema caused by corona virus disease 2019 (COVID-19).

PATIENT CONCERNS

The patient, a young female, developed a fever of 38.7 °C, malaise, and headache, followed by facial edema. After 3 months of conventional treatments (i.e., oral hydroxychloroquine and ebastine) failed, she turned to acupuncture.

DIAGNOSES

Facial edema after COVID-19.

INTERVENTIONS

Acupuncture points on the face (ST2, ST3, ST4, LI20, and SI18), facial acupuncture with multiple micro-needles in the affected area, and distal acupuncture points on LI11, LI4, LI6, SP9, ST36, ST40, and LR3. The patient was treated with acupuncture in 20 sessions over 2 months (3 times a week for the first month, 2 times a week for the second month) and instructed not to use any medication during and after the treatment of acupuncture.

OUTCOMES

After 2 months of acupuncture treatment, the facial edema of the patient subsided.

LESSONS

This case suggests that acupuncture may be an effective alternative therapy for superficial skin inflammation and edema caused by viral infections like COVID-19. Further studies are warranted to explore acupuncture's role in managing post-viral inflammatory conditions.

摘要

原理

新型冠状病毒肺炎(Covid-19)引起的面部皮肤炎症和水肿是一个新问题,尽管仍不太常见。迄今为止,尚无关于使用针灸治疗2019冠状病毒病(COVID-19)引起的面部水肿的报道。

患者情况

患者为年轻女性,出现38.7℃发热、乏力和头痛,随后出现面部水肿。经过3个月的常规治疗(即口服羟氯喹和依巴斯汀)无效后,她转而求助于针灸。

诊断

COVID-19后面部水肿。

干预措施

面部穴位(ST2、ST3、ST4、LI20和SI18)、在患区用多根微针进行面部针刺以及LI11、LI4、LI6、SP9、ST36、ST40和LR3等远端穴位。患者在2个月内接受了20次针灸治疗(第一个月每周3次,第二个月每周2次),并被告知在针灸治疗期间及之后不要使用任何药物。

结果

经过2个月的针灸治疗,患者的面部水肿消退。

经验教训

该病例表明,针灸可能是治疗由COVID-19等病毒感染引起的浅表皮肤炎症和水肿的有效替代疗法。有必要进一步研究以探索针灸在管理病毒感染后炎症性疾病中的作用。

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本文引用的文献

1
Efficacy and Safety of Acupuncture for Post-COVID-19 Insomnia: Protocol for a Systematic Review and Meta-Analysis.针灸治疗新冠后失眠的疗效与安全性:系统评价与荟萃分析方案
JMIR Res Protoc. 2025 Mar 3;14:e69417. doi: 10.2196/69417.
2
Identification of effective synthetic molecules against viral-induced cytokine release syndrome using in silico and in vitro approaches.利用计算机模拟和体外实验方法鉴定抗病毒诱导的细胞因子释放综合征的有效合成分子。
Mol Divers. 2025 Feb 25. doi: 10.1007/s11030-025-11136-3.
3
Hydroxychloroquine: A double‑edged sword (Review).
羟氯喹:一把双刃剑(综述)
Mol Med Rep. 2025 Apr;31(4). doi: 10.3892/mmr.2025.13467. Epub 2025 Feb 21.
4
The effect of pressing needle therapy on depression, anxiety, and sleep for patients in convalescence from COVID-19.揿针疗法对新型冠状病毒肺炎康复期患者抑郁、焦虑及睡眠的影响
Front Neurol. 2024 Dec 18;15:1481557. doi: 10.3389/fneur.2024.1481557. eCollection 2024.
5
Advances in Understanding Diabetic Kidney Disease Progression and the Mechanisms of Acupuncture Intervention.糖尿病肾病进展及针刺干预机制的研究进展
Int J Gen Med. 2024 Nov 27;17:5593-5609. doi: 10.2147/IJGM.S490049. eCollection 2024.
6
Effectiveness and safety of adjunctive non-drug measures in improving respiratory symptoms among patients with severe COVID-19: A multicenter randomized controlled trial.辅助非药物措施改善重症新型冠状病毒肺炎患者呼吸道症状的有效性和安全性:一项多中心随机对照试验
J Integr Med. 2024 Nov;22(6):637-644. doi: 10.1016/j.joim.2024.09.002. Epub 2024 Sep 17.
7
Investigation of the potential molecular mechanisms of acupuncture in the treatment of long COVID: a bioinformatics approach.针刺治疗长新冠的潜在分子机制研究:一种生物信息学方法。
Cell Mol Biol (Noisy-le-grand). 2024 Sep 8;70(8):193-200. doi: 10.14715/cmb/2024.70.8.27.
8
Acupuncture modulation of the ACE/Ang II/AT1R and ACE2/Ang(1-7)/MasR pathways in the rostral ventrolateral medulla reduces sympathetic output and prevents cardiac injury caused by SHR hypertension.针刺调节延髓头端腹外侧区的 ACE/Ang II/AT1R 和 ACE2/Ang(1-7)/MasR 通路,降低交感神经输出,预防 SHR 高血压引起的心脏损伤。
Neuroreport. 2024 Sep 4;35(13):839-845. doi: 10.1097/WNR.0000000000002073. Epub 2024 Jun 29.
9
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Front Neurol. 2024 Apr 16;15:1327206. doi: 10.3389/fneur.2024.1327206. eCollection 2024.
10
Potential mechanisms of acupuncture in enhancing cerebral perfusion of ischemic stroke.针刺增强缺血性脑卒中脑灌注的潜在机制。
Front Neurol. 2022 Oct 28;13:1030747. doi: 10.3389/fneur.2022.1030747. eCollection 2022.