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通过宏基因组二代测序在一名华支睾吸虫病患者中检测到肺部感染：病例报告

Pulmonary Infection Detected via Metagenomic Next-Generation Sequencing in a Clonorchiasis Patient: A Case Report.

作者信息

Wen Sha, Zeng Jing-Jing, Li Ying

机构信息

Department of Critical Care Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, People's Republic of China.

出版信息

Infect Drug Resist. 2024 Nov 25;17:5189-5194. doi: 10.2147/IDR.S481950. eCollection 2024.

DOI:10.2147/IDR.S481950
PMID:39619731
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11606710/
Abstract

() is a Gram-negative obligate intracellular bacterium with a global presence across various hosts, including mammals, humans, and ectoparasites. Herein, we present a case of infection in a previously healthy 43-year-old male with a history of and recent corticosteroid use. The identification of was accomplished through metagenomic next-generation sequencing (mNGS) of the patient's bronchoalveolar lavage fluid (BALF). This case represents the first documented pulmonary infection caused by in China, confirmed by mNGS analysis of bronchoalveolar lavage fluid (BALF) and reported from Shenzhen, China.

摘要

（）是一种革兰氏阴性专性细胞内细菌，广泛存在于包括哺乳动物、人类和体外寄生虫在内的各种宿主中。在此，我们报告一例先前健康的43岁男性感染病例，该患者有（病史）且近期使用过皮质类固醇。通过对患者支气管肺泡灌洗液（BALF）进行宏基因组下一代测序（mNGS）完成了（病原体）的鉴定。该病例是中国首例有文献记载的由（病原体）引起的肺部感染，经支气管肺泡灌洗液（BALF）的mNGS分析证实，并来自中国深圳报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993d/11606710/706cf260dc91/IDR-17-5189-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993d/11606710/316db73b328a/IDR-17-5189-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993d/11606710/706cf260dc91/IDR-17-5189-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993d/11606710/316db73b328a/IDR-17-5189-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993d/11606710/706cf260dc91/IDR-17-5189-g0002.jpg

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