Boyce W H, Kroovand R L
Urol Clin North Am. 1986 May;13(2):307-20.
Twenty-four patients with exstrophy of the urinary bladder (23 patients) or epispadias (1 patient) who were treated by the Boyce-Vest operation have been followed for a total of 482 patient-years (range 3 to 34 years, mean 22 years). In all patients upper urinary morphology and renal function have remained normal, and those with preoperative compromise have stabilized or improved. Postoperatively, no patient has developed an electrolyte imbalance or metabolic acidosis requiring treatment, urinary calculi, or malignant change in the vesicorectal reservoir. Although the procedure and the exstrophy-epispadias complex present many unresolved of management. The infant with exstrophy of the urinary bladder appears best served by early neonatal closure of the exstrophic bladder as described by Jeffs, 6,8 with attempts at establishing urinary continence later in childhood. 6,8,11 When other methods to establish urinary continence are unsuccessful and satisfactory anal continence has been demonstrated, the Boyce-Vest procedure offers an acceptable long-term alternative to establish sphincteric urinary continence. Properly managed, the newborn with uncomplicated exstrophy should have a life expectancy equal to that of any other neonate. More importantly, it is within our ability to provide such patients with adult social acceptability and relative freedom from urinary disease.
24例接受博伊斯-维斯特手术治疗的膀胱外翻患者(23例)或尿道上裂患者(1例),随访时间总计482患者年(范围3至34年,平均22年)。所有患者的上尿路形态和肾功能均保持正常,术前有损害的患者病情已稳定或改善。术后,无患者出现需要治疗的电解质失衡或代谢性酸中毒、尿路结石或膀胱直肠储尿囊恶变。尽管该手术及膀胱外翻-尿道上裂复合体存在许多未解决的管理问题。膀胱外翻患儿最好如杰夫斯所描述的那样,在新生儿期早期关闭外翻膀胱,随后在儿童期尝试建立尿失禁控制。当其他建立尿失禁控制的方法不成功且已证明肛门节制令人满意时,博伊斯-维斯特手术为建立括约肌性尿失禁提供了一种可接受的长期替代方法。管理得当的情况下,单纯膀胱外翻的新生儿预期寿命应与其他新生儿相同。更重要的是,我们有能力为这类患者提供成年后的社会接受度,并使其相对免于泌尿系统疾病。