Maier U, Hofbauer J
Urologe A. 1986 Jan;25(1):33-7.
Seventy-nine patients with urological complications after radiotherapy of their gynecological carcinomas are presented. Twenty-eight patients underwent operation before irradiation. The time between radiotherapy and occurrence of urological complications varied from 0.5 to 27 years (mean 5.3 years). One third of the patients showed a combination of at least two side effects of radiotherapy. There were good results of infiltration therapy with orgotein in patients with radiation cystitis. Because of the unsatisfactory result from primary operation of fistulas, suprapubic urinary diversion is preferred. Gynecologic operation prior to radiotherapy did not influence the results of urological treatment. Seven patients (8.8%) died from urological complications or from complications after urologic treatment. 6 patients (7.6%) showed cancer of the radiated region (3 bladder cancers, 3 colon cancers) within 6 to 20 years after radiotherapy.
本文介绍了79例妇科癌症放疗后出现泌尿系统并发症的患者。28例患者在放疗前接受了手术。放疗与泌尿系统并发症发生之间的时间间隔为0.5至27年(平均5.3年)。三分之一的患者表现出至少两种放疗副作用的组合。辐射性膀胱炎患者采用奥古蛋白进行浸润治疗取得了良好效果。由于瘘管初次手术效果不理想,耻骨上尿路改道是首选方法。放疗前的妇科手术不影响泌尿系统治疗的结果。7例患者(8.8%)死于泌尿系统并发症或泌尿系统治疗后的并发症。6例患者(7.6%)在放疗后6至20年内出现放疗区域癌症(3例膀胱癌,3例结肠癌)。