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[肾癌的放射治疗]

[Radiotherapy of kidney cancer].

作者信息

Schulz U

出版信息

Urologe A. 1986 Jan;25(1):4-6.

PMID:3962042
Abstract

The benefit of low-dose preoperative radiotherapy in hypernephroma has not been proven in phase-II studies. Medium-dose preoperative radiotherapy many transform inoperable to operable tumors in numerous cases. In a randomized study, no prolongation of survival has been found, however. Many retrospective studies, in part with questionable design, have found no value of routinely used postoperative irradiation. Presently, it is indicated in advanced local tumor stages (pT3 and pT4) and residual tumors. Postoperative radiotherapy in high-risk patients using defined techniques and preoperative radiotherapy applying modern diagnostic equipment for treatment planning remains to be evaluated. For palliation, radiotherapy is useful treating brain-, lung- and bone metastases and inoperable primary tumors.

摘要

低剂量术前放疗在肾细胞癌中的益处尚未在II期研究中得到证实。中等剂量的术前放疗在许多情况下可使不可切除的肿瘤转变为可切除肿瘤。然而,在一项随机研究中,未发现生存期延长。许多回顾性研究,部分设计存在问题,未发现常规术后放疗有价值。目前,其适用于局部晚期肿瘤阶段(pT3和pT4)及残留肿瘤。使用明确技术对高危患者进行术后放疗以及应用现代诊断设备进行治疗计划的术前放疗仍有待评估。对于姑息治疗,放疗在治疗脑、肺和骨转移以及不可切除的原发性肿瘤方面很有用。

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