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[肾细胞癌术后放疗结果的回顾性研究]

[A retrospective study of the results of postoperative radiotherapy of hypernephroma].

作者信息

Eilenberger M, Kodym R, Seyss R

机构信息

Universitätsklinik für Strahlentherapie und Strahlenbiologie Wien.

出版信息

Radiobiol Radiother (Berl). 1990;31(6):491-6.

PMID:2101453
Abstract

Retrospectively the patients were analyzed, postoperatively irradiated because of a hypernephroidal kidney carcinoma during the years 1978 to 1988. With a total number of 44 patients 12 were in stage I (Robson), 13 in stage II, 17 in stage III and 2 in stage IV. The probabilities for a tumor-free survival of five years were 81%, 59% and 30% for the stages I to III. The local recurrence rate was 7%, caused by exclusion of clinically negative lymph-nodes from irradiation field. In addition to survival probabilities the complication rate of radiotherapy is analyzed too. To this additionally to analysis of symptoms of a possible side-effect the nuclear medical investigation of function of the remaining kidney was done in 9 selected tumor-free patients being irradiated in different techniques. A normal function was found in all cases. No severe side-effects can be shown in irradiated patients. Consequently the postoperative radiotherapy in hypernephroma is a supportive therapy of advanced tumor stages without severe side-effects. Further and greater planned analyses are necessary to comprehend prognostic factors.

摘要

对1978年至1988年间因肾细胞癌接受术后放疗的患者进行回顾性分析。总共有44例患者,其中I期(罗布森分期)12例,II期13例,III期17例,IV期2例。I至III期患者的五年无瘤生存率分别为81%、59%和30%。局部复发率为7%,原因是放疗野未包括临床阴性淋巴结。除了分析生存概率外,还分析了放疗的并发症发生率。此外,除了分析可能的副作用症状外,还对9例采用不同技术进行放疗且无瘤的选定患者进行了剩余肾脏功能的核医学检查。所有病例均发现功能正常。放疗患者未出现严重副作用。因此,肾细胞癌术后放疗是晚期肿瘤阶段的一种支持性治疗,且无严重副作用。需要进一步进行更有计划的分析以了解预后因素。

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