Semenovskiĭ A V
Vopr Onkol. 1986;32(3):23-7.
An analysis of the results of uterine choriocarcinoma treatment versus the degree of risk is presented. Chemotherapy alone was found to be sufficient in 70.2% of cases free of risk, as compared with only 31.2% in case of four and more factors. Application of chemotherapy alone proved, on the whole, to be more beneficial than that of surgery plus chemotherapy modality, as evidenced by the death rates of 13.8 +/- 3.4 and 32.5 +/- 5.4% (t = 2.9), respectively. Polychemotherapy of cases with 1-4 factors of risk or more gave significantly better results than monochemotherapy, regardless of the former being a sole treatment or a component of combined therapy.
本文对子宫绒毛膜癌治疗结果与风险程度进行了分析。结果发现,在无风险的病例中,70.2%仅采用化疗就足够了,而在有四个及以上风险因素的病例中,这一比例仅为31.2%。总体而言,仅化疗的应用比手术加化疗方式更有益,分别为13.8 +/- 3.4%和32.5 +/- 5.4%的死亡率(t = 2.9)证明了这一点。无论单药化疗是作为单一治疗还是联合治疗的一部分,对于有1 - 4个或更多风险因素的病例,多药化疗的效果都明显优于单药化疗。