Tarlowska L, Czesnin K, Psikuta M, Romejko M
Vopr Onkol. 1986;32(3):36-44.
The results of combined treatment (surgery and postoperative radiotherapy) in the group of 240 patients with stage I and II ovarian carcinoma were evaluated. The following factors were found to be important for prognosis: (I) removal of clinically detectable cancer sites during primary surgery (60.7% of 5-year survivals versus 19.4% of cases of surgery described by the surgeon as non-radical); (2) stage of tumor: 62.2% of survivals at stage I as compared with 28.3% at stage II; 73.9% at stage I without changes in the capsule of tumor against 56.9% in the other groups with the same stage; 45.5% at stage IIa versus 22.9% at stages IIb and IIc; (3) low differentiation of ovarian carcinoma which reduces curability to 44.9% in cases of stage I and IIa tumors. Five-year survival rates were higher, though statistically insignificant in those patients with stage Ia(i) and Ib(i) in whom intravaginal radium was applied (81.8%), and in those with stages Ia(ii), Ib(ii) and Ic in whom the whole abdomen was irradiated (64.5%). No statistically significant differences in relation to age, type of surgery, size of tumor identified during the first operation or type of teleradiotherapy (conventional roentgenotherapy or telecobalt therapy) were found.