Tarlowska L, Czesnin K, Psikuta M, Romejko M
Vopr Onkol. 1986;32(3):36-44.
The results of combined treatment (surgery and postoperative radiotherapy) in the group of 240 patients with stage I and II ovarian carcinoma were evaluated. The following factors were found to be important for prognosis: (I) removal of clinically detectable cancer sites during primary surgery (60.7% of 5-year survivals versus 19.4% of cases of surgery described by the surgeon as non-radical); (2) stage of tumor: 62.2% of survivals at stage I as compared with 28.3% at stage II; 73.9% at stage I without changes in the capsule of tumor against 56.9% in the other groups with the same stage; 45.5% at stage IIa versus 22.9% at stages IIb and IIc; (3) low differentiation of ovarian carcinoma which reduces curability to 44.9% in cases of stage I and IIa tumors. Five-year survival rates were higher, though statistically insignificant in those patients with stage Ia(i) and Ib(i) in whom intravaginal radium was applied (81.8%), and in those with stages Ia(ii), Ib(ii) and Ic in whom the whole abdomen was irradiated (64.5%). No statistically significant differences in relation to age, type of surgery, size of tumor identified during the first operation or type of teleradiotherapy (conventional roentgenotherapy or telecobalt therapy) were found.
对240例I期和II期卵巢癌患者的联合治疗(手术及术后放疗)结果进行了评估。发现以下因素对预后很重要:(1)初次手术时切除临床上可检测到的癌灶(5年生存率为60.7%,而外科医生描述为非根治性手术的病例为19.4%);(2)肿瘤分期:I期生存率为62.2%,II期为28.3%;I期肿瘤包膜无变化者生存率为73.9%,同分期其他组为56.9%;IIa期为45.5%,IIb期和IIc期为22.9%;(3)卵巢癌低分化,I期和IIa期肿瘤患者的治愈率降至44.9%。Ia(i)期和Ib(i)期应用阴道镭疗的患者(81.8%)以及Ia(ii)期、Ib(ii)期和Ic期进行全腹照射的患者5年生存率较高,尽管无统计学意义。在年龄、手术类型、首次手术时发现的肿瘤大小或远距离放射治疗类型(传统X线治疗或钴远距离治疗)方面未发现统计学上的显著差异。