Berdinskikh N K, Lialiushko N M
Vopr Onkol. 1986;32(3):80-5.
The paper deals with an evaluation of the levels of polyamines (putrescin, spermidine and spermine) in the liver tissue of rats bearing Guerin's carcinoma, after injection of blood serum proteins and glucose. Tumor growth was followed by an increase in polyamine levels in the liver tissue of tumor-bearing rats. Injection of blood serum or glucose prevented the development of the said changes. It was inferred that tumor-induced changes in polyamine profile of the host liver are nonspecific. They are compensatory and intended for correction of homeostasis of the host.
本文探讨了在注射血清蛋白和葡萄糖后，荷Guerin癌大鼠肝脏组织中多胺（腐胺、亚精胺和精胺）水平的评估情况。肿瘤生长伴随着荷瘤大鼠肝脏组织中多胺水平的升高。注射血清或葡萄糖可阻止上述变化的发生。据推测，肿瘤诱导的宿主肝脏多胺谱变化是非特异性的。它们具有代偿性，旨在纠正宿主的稳态。
