青霉素过敏诊断中皮肤试验的价值。
The value of skin testing for penicillin allergy diagnosis.
作者信息
VanArsdel P P, Martonick G J, Johnson L E, Sprenger J D, Altman L C, Henderson W R
出版信息
West J Med. 1986 Mar;144(3):311-4.
Skin testing is reliable and useful to rule out penicillin allergy in most patients who have a history of previous reactions. When we tested 291 inpatients in the University of Washington hospitals for the presence or absence of penicillin allergy, of 97 with a history of penicillin allergy, 12 (12.4%) had positive skin tests. Of 194 patients with no or an unknown history, only 4 (2%) had positive skin tests. Two of the 16 who had positive skin tests (12.5%) reacted only to minor determinant mixtures. Of the skin test-negative patients, 261 were treated with one of the penicillins and only two had any reactions.
皮肤试验对于排除大多数有既往反应史患者的青霉素过敏是可靠且有用的。当我们在华盛顿大学医院对291名住院患者进行青霉素过敏情况检测时，97名有青霉素过敏史的患者中，12名（12.4%）皮肤试验呈阳性。194名无过敏史或过敏史不明的患者中，只有4名（2%）皮肤试验呈阳性。16名皮肤试验呈阳性的患者中有2名（12.5%）仅对次要决定簇混合物有反应。在皮肤试验阴性的患者中，261名接受了一种青霉素治疗，只有2名出现了任何反应。
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