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医院痴呆症护理项目对医院获得性并发症的影响——一项非随机阶梯楔形混合效果-实施研究。

The impact of the Dementia Care in Hospitals Program on hospital acquired complications - a non-randomised stepped wedge hybrid effectiveness-implementation study.

作者信息

Yates Mark W, Bail Kasia, MacDermott Sean, Skvarc David, Theobald Meredith, Morvell Michelle, Jebramek Jessica C, Tebbut Ian, Draper Brian, Brodaty Henry

机构信息

Grampians Health, Ballarat Health Services, School of Medicine, Faculty of Health, Deakin University, Ballarat, VIC, Australia.

Ageing Research Group, Faculty of Health, Synergy Nursing and Midwifery Research Centre ACT Health, University of Canberra, Canberra, Australia.

出版信息

BMC Geriatr. 2024 Dec 2;24(1):986. doi: 10.1186/s12877-024-05548-3.

Abstract

BACKGROUND

Hospitalized older patients with cognitive impairment (CI) experience poor outcomes and high rates of hospital acquired complications (HACs). This study investigated the effectiveness of a multimodal hospital CI identification and education program.

METHOD

A prospective stepped-wedge, cross-sectional, continuous-recruitment, hybrid effectiveness-Implementation study was conducted in acute hospitals in four Australian states/territories. The intervention, the Dementia Care in Hospitals Program (DHCP) provided: clinical/ non-clinical hospital staff CI awareness support and education; CI screening for older patients and a bedside alert-the Cognitive Impairment Identifier (CII). The primary outcome was change in the rate of the combined risk of four HACs (urinary tract infection, pneumonia, new onset delirium, pressure injury).

RESULTS

Participants were patients aged 65 years and over admitted for 24 h or more over a 12-month period between 2015-2017 (n = 16,789). Of the 11,309 (67.4%) screened, 4,277 (37.8%) had CI. HACs occurred in 27.4% of all screened patients and were three times more likely in patients with CI after controlling for age and sex (RR = 3.03; 95%CI:2.74-3.27). There was no significant change in HAC rate for patients with CI (RR = 1.084; 95%CI: 0.93; 1.26). In the intervention period the raw HAC rate for all screened patients was 27.0%, which when adjusted for age and sex suggested a small reduction overall. However, when adjusted for hospital site, this reduction in HAC risk not statistically significant (RR = 0.968; 95%CI:0.865-1.083). There was considerable interhospital variation in intervention implementation and outcomes which explains the final non-significant effect.

CONCLUSION

For patient with CI the implementation of the DCHP did not result in a reduction in HAC rates. Education for hospital staff regarding cognitive impairment screening, care support, carer engagement and bedside alerts, using the DCHP, can be feasibly implemented in acute hospitals. Reducing high frequency HACs in older hospital patients with CI, warrants further research.

TRIAL REGISTRATION

The trial was registered retrospectively with the Australian New Zealand Clinical Trials Registry (ANZCTR) ACTRN12615000905561 on 01/09/2015 with 92 patients (0.8% of total sample) recruited in the baseline and none in the intervention before registration submission.

摘要

背景

住院的认知障碍(CI)老年患者预后较差,医院获得性并发症(HACs)发生率较高。本研究调查了一项多模式医院CI识别与教育计划的有效性。

方法

在澳大利亚四个州/领地的急性医院进行了一项前瞻性阶梯楔形、横断面、连续招募的混合有效性-实施研究。干预措施为医院痴呆症护理计划(DHCP),提供:临床/非临床医院工作人员CI意识支持与教育;对老年患者进行CI筛查以及床边警报器——认知障碍识别器(CII)。主要结局是四种HACs(尿路感染、肺炎、新发谵妄、压疮)综合风险率的变化。

结果

研究对象为2015年至2017年期间12个月内入院24小时及以上的65岁及以上患者(n = 16,789)。在11,309名(67.4%)接受筛查的患者中,4,277名(37.8%)有CI。所有接受筛查的患者中,27.4%发生了HACs,在控制年龄和性别后,CI患者发生HACs的可能性是其他患者的三倍(相对风险RR = 3.03;95%置信区间:2.74 - 3.27)。CI患者的HAC率没有显著变化(RR = 1.084;95%置信区间:0.93;1.26)。在干预期,所有接受筛查患者的原始HAC率为27.0%,经年龄和性别调整后总体略有下降。然而,经医院地点调整后,HAC风险的这种降低无统计学意义(RR = 0.968;95%置信区间:0.865 - 1.083)。干预措施的实施和结局在不同医院间存在很大差异,这解释了最终无显著效果的原因。

结论

对于CI患者,实施DHCP并未降低HAC率。利用DHCP对医院工作人员进行认知障碍筛查、护理支持、照顾者参与及床边警报方面的教育,在急性医院中可以切实可行地实施。降低老年CI住院患者的高频HACs,值得进一步研究。

试验注册

该试验于2015年9月1日在澳大利亚新西兰临床试验注册中心(ANZCTR)进行回顾性注册,注册号为ACTRN12615000905561,基线期招募了92名患者(占总样本的0.8%),在注册提交前的干预期未招募患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9059/11610119/4be8d585d7eb/12877_2024_5548_Fig1_HTML.jpg

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