Wang Zixin, Chen Siyu, Wong Ngai Sze, Cheung Annie Wai-Ling, Tam Zoe Pui-Yee, Chung Sze Long, Chan Denise Pui-Chung, Mo Phoenix K H, Wong Eliza Lai-Yi
Centre for Health Behaviours Research, JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China.
Faculty of Medicine, the Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong SAR, China.
BMC Med. 2024 Dec 2;22(1):569. doi: 10.1186/s12916-024-03788-z.
Human papillomavirus (HPV) infection is prevalent among people who are sexually active. This study aimed to compare the levels of behavioral intention to receive free clinician-collected and self-collected samples for HPV DNA testing and its determinants between heterosexual males and females in Hong Kong, China.
This is a secondary analysis of a territory-wide survey conducted in Hong Kong between May 2021 and March 2022. Participants were sexually active adult Hong Kong residents who were able to communicate in English or Chinese. Invitation letters were mailed to residential addresses that were geographically randomly selected. All sexually active adult household members were invited to complete a self-administered online survey. Multivariate logistic regression analyses were fitted.
Out of 45,394 invitations, 1265 surveys were collected, and 487 heterosexual males and 741 females were included in the analysis. More females than heterosexual males intended to take up free clinician-collected samples for HPV DNA testing (76.7% versus 62.2%, p < 0.001). Similar proportion of heterosexual males and females intended to receive free self-collected samples for HPV DNA testing (67.8% versus 72.6%, p = 0.20). Perceived existing treatment could control sexually transmitted infections (STI) (treatment control), more concerned about STI (concern), perceived more benefits, cue to action (suggested by significant others), and self-efficacy related to HPV testing were associated with higher intention to receive clinician-collected samples for HPV testing in both groups. Heterosexual males who perceived more severe symptoms if contracted STI (identity), longer duration of STI (timeline), more negative effects of STI on their lives (consequences), more understanding of STI (coherence), and stronger negative emotions if contracted STI (emotions) also had higher behavioral intention to take up clinician-collected samples for HPV testing. In addition, perceived more benefits, cue to action, and self-efficacy related to self-collected samples for HPV DNA testing were associated with behavioral intention to take up such testing in both groups.
HPV DNA testing was under-utilized in Hong Kong. Free self-collected samples for HPV testing were highly acceptable by both heterosexual males and females. Illness representation of STI and the Health Belief Model could explain intentions to take up HPV DNA testing.
人乳头瘤病毒（HPV）感染在性活跃人群中很普遍。本研究旨在比较中国香港异性恋男性和女性接受免费临床医生采集样本及自我采集样本进行HPV DNA检测的行为意愿水平及其决定因素。
这是对2021年5月至2022年3月在香港进行的一项全地区调查的二次分析。参与者为能够用英语或中文交流的性活跃成年香港居民。邀请函被邮寄到地理上随机选择的居住地址。所有性活跃的成年家庭成员都被邀请完成一份自我管理的在线调查。进行了多变量逻辑回归分析。
在45394份邀请函中，收集到1265份调查问卷，487名异性恋男性和741名女性被纳入分析。打算接受免费临床医生采集样本进行HPV DNA检测的女性多于异性恋男性（76.7%对62.2%，p<0.001）。打算接受免费自我采集样本进行HPV DNA检测的异性恋男性和女性比例相似（67.8%对72.6%，p = 0.20）。两组中，感知到现有治疗可控制性传播感染（STI）（治疗控制）、更关注性传播感染（关注）、感知到更多益处、行动提示（重要他人建议）以及与HPV检测相关的自我效能感与接受临床医生采集样本进行HPV检测的更高意愿相关。如果感染性传播感染会感知到更严重症状（身份）、性传播感染持续时间更长（时间线）、性传播感染对其生活的负面影响更大（后果）、对性传播感染有更多了解（连贯性）以及如果感染性传播感染会有更强烈负面情绪（情绪）的异性恋男性接受临床医生采集样本进行HPV检测的行为意愿也更高。此外，两组中，感知到更多益处、行动提示以及与自我采集样本进行HPV DNA检测相关的自我效能感与接受此类检测的行为意愿相关。
HPV DNA检测在香港未得到充分利用。免费自我采集样本进行HPV检测受到异性恋男性和女性的高度认可。性传播感染的疾病表征和健康信念模型可以解释接受HPV DNA检测的意愿。
