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酷似前列腺癌的严重黄色肉芽肿性前列腺炎:一例报告

Severe Xanthogranulomatous prostatitis mimicking prostate cancer: a case report.

作者信息

Hassan Wael Abdo, Elmetwally Ahmed Ali, Abdelhafeez Mennat Allah Mohammed, Ali Osama Khalid Abo

机构信息

Department of Pathology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

Department of Basic Sciences, College of Medicine, Suliman Al Rajhi University, P. O. Box 777, 51941, Al Bukairiyah, Saudi Arabia.

出版信息

J Med Case Rep. 2024 Dec 3;18(1):582. doi: 10.1186/s13256-024-04870-z.

DOI:10.1186/s13256-024-04870-z
PMID:39623396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11613866/
Abstract

BACKGROUND

Xanthogranulomatous prostatitis is a rare, noncancerous inflammatory condition of the prostate that clinically resembles prostatic carcinoma, necessitating a pathological examination for accurate diagnosis.

CASE PRESENTATION

A 75-year-old Egyptian male presented with urinary symptoms and an elevated serum prostate-specific antigen. Initial clinical and imaging findings suggested a locally advanced carcinoma of the prostate. However, histopathological examination after transurethral resection of the prostate revealed severe xanthogranulomatous prostatitis on a background of benign prostatic hyperplasia.

CONCLUSION

Xanthogranulomatous prostatitis can present with symptoms and radiological findings and biochemical markers similar to those of prostatic carcinoma. Accurate diagnosis of xanthogranulomatous prostatitis requires a high level of suspicion and close collaboration with a pathologist.

摘要

背景

黄色肉芽肿性前列腺炎是一种罕见的前列腺非癌性炎症性疾病,临床上类似于前列腺癌,需要进行病理检查以准确诊断。

病例报告

一名75岁的埃及男性出现泌尿系统症状,血清前列腺特异性抗原升高。最初的临床和影像学检查结果提示为局部晚期前列腺癌。然而,经尿道前列腺切除术后的组织病理学检查显示,在良性前列腺增生的背景下存在严重的黄色肉芽肿性前列腺炎。

结论

黄色肉芽肿性前列腺炎可表现出与前列腺癌相似的症状、影像学检查结果和生化指标。准确诊断黄色肉芽肿性前列腺炎需要高度的怀疑,并与病理学家密切合作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42d0/11613866/2484973d3111/13256_2024_4870_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42d0/11613866/87613664c4c4/13256_2024_4870_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42d0/11613866/2484973d3111/13256_2024_4870_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42d0/11613866/87613664c4c4/13256_2024_4870_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42d0/11613866/2484973d3111/13256_2024_4870_Fig2_HTML.jpg

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本文引用的文献

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High expression of Trop2 is associated with aggressive localized prostate cancer and is a candidate urinary biomarker.Trop2 的高表达与侵袭性局限性前列腺癌相关,是候选的尿生物标志物。
Sci Rep. 2024 Jan 4;14(1):486. doi: 10.1038/s41598-023-50215-z.
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Granulomatous and xanthogranulomatous prostatitis: A case report.肉芽肿性和黄色肉芽肿性前列腺炎:一例报告
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Xanthogranulomatous Prostatitis: Novel Presentation of a Rare Condition.黄色肉芽肿性前列腺炎:一种罕见疾病的新表现。
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An improbable trifecta: Occurrence of xanthogranulomatous prostatitis, prostate cancer, and prostatic abscess in a single patient.一个罕见的三重奏:一名患者同时出现黄色肉芽肿性前列腺炎、前列腺癌和前列腺脓肿。
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Nucleolin and Nucleophosmin Expression in Gleason 3 and Gleason 4 Prostate Cancer With Seminal Vesicles Invasion (pT3b).核仁素和核仁磷酸蛋白在伴有精囊侵犯(pT3b)的 Gleason3 和 Gleason4 前列腺癌中的表达。
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Xanthogranulomatous prostatitis presenting as prostatic abscesses: An uncommon complication after kidney transplantation.表现为前列腺脓肿的黄色肉芽肿性前列腺炎:肾移植后一种罕见的并发症。
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Hematospermia and xanthogranulomatous prostatitis: An unusual onset of a rare diagnosis.血精症与黄色肉芽肿性前列腺炎:一种罕见诊断的不寻常发病情况。
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Zhonghua Nan Ke Xue. 2013 Feb;19(2):149-52.
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