Kim Jung Eun, Lee Subin, Kang Hoon, Lee Young, Kim Do-Young, Park Hyunsun, Shin Hyun-Tae, Jang Yong Hyun, Shin Kihyuk, Lee Ji Hae, Choi Jee Woong, Park Byung Choel, Kim Beom Joon, Seo Soo Hong, Won Chong Hyun, Park Jin, Kim Min Sung, Kim Sang Seok, Lew Bark-Lynn, Huh Chang-Hun, Kwon Ohsang, Lee Yang Won, Kim Moon-Bum
Department of Dermatology, The Catholic University of Korea, College of Medicine, Seoul, Korea.
Department of Dermatology, Chungnam National University School of Medicine, Daejeon, Korea.
Ann Dermatol. 2024 Dec;36(6):376-383. doi: 10.5021/ad.24.033.
Alopecia areata (AA) is characterized by hair loss on the scalp and body, significantly impacting patients' quality of life based on its severity.
This study aims to identify crucial factors influencing the perception of severe AA from the patients' viewpoint.
A web-based survey was conducted among AA patients attending dermatology departments at 21 university hospitals in Korea. The survey comprised 17 criteria, exploring both clinical characteristics of AA patients and subjective determinants of disease severity.
A total of 791 AA patients and their caregivers participated in the survey. Approximately 30% of respondents developed AA during childhood, with 43.5% experiencing chronic courses lasting over 3 years. Half of the participants exhibited more than 20% scalp hair loss, and 42% reported additional hair loss on other body parts, such as eyelashes and nose hair. Most respondents agreed that patients with ≥20% scalp hair loss should be categorized as having severe AA. They also identified longer disease duration, involvement of non-scalp body hair, treatment refractoriness, and social or mental impairment requiring medical intervention as factors indicating increased disease severity.
This survey underscores the significant impact of AA on patients' quality of life and highlights existing unmet needs in current treatment modalities.
斑秃（AA）的特征是头皮和身体毛发脱落，根据其严重程度对患者的生活质量有显著影响。
本研究旨在从患者的角度确定影响重度斑秃认知的关键因素。
在韩国21所大学医院皮肤科就诊的斑秃患者中进行了一项基于网络的调查。该调查包括17项标准，探讨了斑秃患者的临床特征和疾病严重程度的主观决定因素。
共有791名斑秃患者及其护理人员参与了调查。约30%的受访者在儿童时期患上斑秃，43.5%经历了持续超过3年的慢性病程。一半的参与者头皮脱发超过20%，42%报告身体其他部位如睫毛和鼻毛也有额外脱发。大多数受访者同意，头皮脱发≥20%的患者应被归类为重度斑秃。他们还确定病程较长、非头皮身体毛发受累、治疗难治性以及需要医疗干预的社会或心理障碍是疾病严重程度增加的指标。
本次调查强调了斑秃对患者生活质量的重大影响，并突出了当前治疗方式中存在的未满足需求。
