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通过移动健康干预改善与食物相关的抑制控制——一项随机对照试验的次要结果分析

Improving Food-Related Inhibitory Control Through an mHealth Intervention-A Secondary Outcome Analysis of an RCT.

作者信息

Schoemann Natalie, Seiferth Caroline, Pape Magdalena, Färber Tanja, Herpertz Stephan, Steins-Loeber Sabine, Wolstein Jörg

机构信息

Department of Psychopathology University of Bamberg Bamberg Germany.

Division of Clinical Psychology and Psychotherapy Freie Universität Berlin Berlin Germany.

出版信息

Obes Sci Pract. 2024 Dec 2;10(6):e70026. doi: 10.1002/osp4.70026. eCollection 2024 Dec.

Abstract

BACKGROUND

Experimental studies reveal that deficits in food-related inhibitory control, rather than general impulsiveness, are closely linked to overweight and obesity. To date, the real-world implications remain unknown, and it is unclear whether these results are supported in the clinical field.

OBJECTIVE

To examine the effectiveness of a mobile health (mHealth) intervention with cognitive and behavioral therapeutic elements in altering impulsiveness and food-related inhibitory control.

METHODS

Prespecified secondary outcome analysis of a randomized controlled trial. Participants with overweight/obesity (BMI:  = 33.35 kg/m, SD = 3.79 kg/m,  = 213) were randomly assigned to either a 12-week mHealth intervention ( = 116) or wait-list control group ( = 97). The Barratt-Impulsiveness-Scale (BIS-15) and the Food-Related Inhibitory Control Scale (FRIS) were administered at baseline (T0) following the intervention (T1), at 9 and 15 month post baseline (T2, T3). Multi-level analyses were calculated.

RESULTS

Compared to the control group, the intervention group reported higher food-related inhibitory control on several subscales of the FRIS: In Withholding in Social Situations at T1 (95% CI: 0.06-0.46) and T2 (95%CI: 0.09-0.50), Action Cancellation at T1 (95%CI: 0.05-0.45), Resisting despite Craving at T1 (95% CI: 0.07-0.49), Withstanding Rewarding Food at T2 (95%CI: 0.08-0.55) and Action Withholding at T3 (95% CI: 0.01-0.55). No differences were found for trait impulsiveness (T1: 95%CI: -1.91-0.47; T2: 95%CI: -1.65-0.84; T3: 95%CI: -0.88-1.67).

CONCLUSIONS

Food-related inhibitory control, rather than global measures of impulsiveness, addresses the critical association between inhibitory control and health-conscious dietary choices and can be improved by mHealth intervention.

TRIAL REGISTRATION

ClinicalTrials.gov identifier: NCT04080193.

摘要

背景

实验研究表明,与食物相关的抑制控制缺陷而非一般冲动性与超重和肥胖密切相关。迄今为止,其在现实世界中的影响尚不清楚,这些结果在临床领域是否得到支持也不明确。

目的

研究一种具有认知和行为治疗元素的移动健康(mHealth)干预措施在改变冲动性和与食物相关的抑制控制方面的有效性。

方法

对一项随机对照试验进行预先指定的次要结果分析。超重/肥胖参与者(BMI:= 33.35 kg/m,标准差 = 3.79 kg/m,= 213)被随机分配到为期12周的mHealth干预组(= 116)或等待名单对照组(= 97)。在基线(T0)、干预后(T1)、基线后9个月和15个月(T2、T3)时使用巴拉特冲动量表(BIS - 15)和与食物相关的抑制控制量表(FRIS)进行测量。进行多层次分析。

结果

与对照组相比,干预组在FRIS的几个子量表上报告了更高的与食物相关的抑制控制:在T1(95%置信区间:0.06 - 0.46)和T2(95%置信区间:0.09 - 0.50)的社交情境中抑制、T1时的行动取消(95%置信区间:0.05 - 0.45)、T1时尽管渴望仍抵抗(95%置信区间:0.07 - 0.49)、T2时耐受诱人食物(95%置信区间:0.08 - 0.55)以及T3时行动抑制(95%置信区间:0.01 - 0.55)。特质冲动性方面未发现差异(T1:95%置信区间: - 1.91 - 0.47;T2:95%置信区间: - 1.65 - 0.84;T3:95%置信区间: - 0.88 - 1.67)。

结论

与食物相关的抑制控制而非冲动性的整体测量,解决了抑制控制与注重健康的饮食选择之间的关键关联,并且可以通过mHealth干预得到改善。

试验注册

ClinicalTrials.gov标识符:NCT04080193。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef3/11609755/b2aa87deab4b/OSP4-10-e70026-g002.jpg

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