Sasaki Yusuke, Otsuka Yukiko, Matsunami Kunihiro, Miyazaki Kumiko, Matsukuma Eiji, Imamura Atsushi, Kaneko Hideo
Department of Pediatrics, Gifu Prefectural General Medical Center, Gifu, Japan.
Department of Pediatric Medical Care, Gifu Prefectural General Medical Center, Gifu, Japan.
Asia Pac Allergy. 2024 Dec;14(4):220-222. doi: 10.5415/apallergy.0000000000000143. Epub 2024 Apr 3.
Peanut allergy is a common food allergy. Accidental peanut exposure can induce anaphylactic symptoms in allergic individuals. In rare cases, pancreatitis can be induced by food allergies. This report describes a 12-year-old girl with recurrent acute pancreatitis (AP) following a peanut allergy induced 8 years after the first episode. The patient experienced the first episode of AP at 4 years old when she accidentally consumed peanut powder ice cream. AP was recurrently induced 8 years later by an oral food challenge test with a small amount of peanuts, despite decreased specific IgE for peanuts and Arah2. This report is the first to demonstrate that AP, as a peanut-induced symptom, is difficult to tolerate over a long period in a patient with peanut allergy. The possibility of AP induction after accidental ingestion, oral food challenge, or oral immunotherapy for peanuts should be considered in patients with peanut allergy.
花生过敏是一种常见的食物过敏。过敏个体意外接触花生可诱发过敏症状。在罕见情况下，食物过敏可诱发胰腺炎。本报告描述了一名12岁女孩，在首次发作花生过敏8年后出现复发性急性胰腺炎（AP）。患者4岁时意外食用花生粉冰淇淋，经历了首次AP发作。8年后，尽管花生特异性IgE和Ara h2有所下降，但通过口服少量花生进行食物激发试验仍再次诱发了AP。本报告首次证明，作为花生诱发症状的AP，在花生过敏患者中很难长期耐受。花生过敏患者应考虑意外摄入、口服食物激发试验或花生口服免疫治疗后诱发AP的可能性。
