Calkins Daniel, Cabrera Cancio Margarita R, Mayer Cynthia A, Mackie Benjamin
Infectious Diseases, University of South Florida Morsani College of Medicine, Tampa, USA.
Transplant Infectious Disease, Infectious Disease Associates of Tampa Bay, Tampa, USA.
Cureus. 2024 Nov 2;16(11):e72887. doi: 10.7759/cureus.72887. eCollection 2024 Nov.
Atypical mycobacterium infections are an uncommon cause of cutaneous infection, and they are especially rare infections of the facial region. Immunocompromised patients, such as transplant patients, are at higher risk for infections of this nature with concurrent hematogenous spread to other organ systems. We report a patient with a previous heart transplant who developed an atypical mycobacterium infection of the skin with possible dissemination to the lung. The case outlines the difficulty in diagnosing this condition along with the challenges of prescribing an effective drug regimen to treat this infection. Azithromycin, minocycline, rifabutin, and high-dose ethambutol were effective in clearing the skin and lung lesions.
非典型分枝杆菌感染是皮肤感染的罕见病因，在面部区域感染尤为少见。免疫功能低下的患者，如移植患者，发生此类感染并同时血行播散至其他器官系统的风险更高。我们报告一例曾接受心脏移植的患者，其发生了皮肤非典型分枝杆菌感染并可能播散至肺部。该病例概述了诊断这种疾病的困难以及制定有效药物治疗方案来治疗这种感染所面临的挑战。阿奇霉素、米诺环素、利福布汀和高剂量乙胺丁醇在清除皮肤和肺部病变方面有效。
