Raza Qaisar, Hina Rashk-E, Nawaz Sadia, Safdar Minahil, Imran Kinza, Ashraf Urwah, Imran Muhammad Saeed
Department of Food Science and Human Nutrition, University of Veterinary and Animal Sciences, Lahore, PAK.
Department of Genetics, University of Veterinary and Animal Sciences, Lahore, PAK.
Cureus. 2024 Nov 2;16(11):e72886. doi: 10.7759/cureus.72886. eCollection 2024 Nov.
Acne is significantly influenced by glycemic load (GL), which is the result of the quantity of carbohydrates consumed and how quickly they are metabolized. There is an association between high-GL foods and severe acne. Such diets increase insulin and insulin-like growth factor 1 (IGF-1) levels, which then stimulate sebum production and androgen hormone release, which ultimately results in the development of acne. Previous studies have shown a high prevalence of acne in South Asia, but there is a lack of study on acne and its determinants among females in Pakistan.
This study aims to assess the effect of low-glycemic index foods and dietary counseling in potentially improving the quality of life of female acne patients and reducing post-acne lesions and the severity of the disease.
The sample size consisted of 50 females aged 15-35 years. The study aimed to see how a low-GL diet could affect the severity of acne. The trial included 50 participants, split into two groups: 25 in the control group and 25 in the treatment group. The trial went on for 12 weeks and used a food questionnaire to gather data each month. Participants were given scores based on how much high-GL food they ate. The score range between 0 and 35 showed a low intake of high-GL foods, and a score range between 35 and 55 was considered to be the average intake of high-GL foods. A score range between 55 and 75 showed a very high intake of high-GL foods. Higher scores indicated higher GL food consumption.
In the control group, after one month, 18 participants (70%) had GL scores above 55, which correlated with higher acne severity. In contrast, only three participants (12%) had low-GL scores (0-35). The treatment group showed significant improvement; initially, 15 participants (60%) had high-GL scores, but this number decreased to nine participants (40%) by the end of the study. After three months, 10 participants (45%) in the treatment group achieved low-GL scores (0-35), compared to only two participants (10%) in the control group. This improvement was accompanied by a decrease in average acne severity from 2.68 to 1.56 and an increase in water intake and promoted better skin health among females.
Dietary counseling along with low-GL foods can improve acne severity and lesions in adult females. This treatment also enhanced self-confidence and social acceptance.
血糖负荷(GL)对痤疮有显著影响,血糖负荷是所摄入碳水化合物的量及其代谢速度的结果。高血糖负荷食物与重度痤疮之间存在关联。这类饮食会提高胰岛素和胰岛素样生长因子1(IGF-1)的水平,进而刺激皮脂分泌和雄激素释放,最终导致痤疮的形成。此前的研究表明,南亚地区痤疮的患病率较高,但在巴基斯坦女性中,关于痤疮及其决定因素的研究较少。
本研究旨在评估低血糖指数食物和饮食咨询对潜在改善女性痤疮患者生活质量、减少痤疮后瘢痕及疾病严重程度的效果。
样本为50名年龄在15至35岁之间的女性。该研究旨在观察低血糖负荷饮食如何影响痤疮的严重程度。试验包括50名参与者,分为两组:对照组25人,治疗组25人。试验持续12周,每月使用食物问卷收集数据。根据参与者高血糖负荷食物的摄入量为其打分。分数在0至35分之间表明高血糖负荷食物摄入量低,35至55分之间被认为是高血糖负荷食物的平均摄入量。分数在55至75分之间表明高血糖负荷食物摄入量非常高。分数越高表明高血糖负荷食物的消费量越高。
在对照组中,一个月后,18名参与者(70%)的血糖负荷分数高于55分,这与痤疮严重程度较高相关。相比之下,只有3名参与者(12%)的血糖负荷分数较低(0至35分)。治疗组有显著改善;最初,15名参与者(60%)的血糖负荷分数较高,但到研究结束时,这一数字降至9名参与者(40%)。三个月后,治疗组有10名参与者(45%)的血糖负荷分数较低(0至35分),而对照组只有2名参与者(10%)。这种改善伴随着平均痤疮严重程度从2.68降至1.56,饮水量增加,并促进了女性更好的皮肤健康。
饮食咨询与低血糖负荷食物相结合可以改善成年女性的痤疮严重程度和瘢痕。这种治疗方法还增强了自信心和社会认可度。