Sheppard Rory, Gan Weh K, Onambele-Pearson Gladys L, Young Helen S
Division of Musculoskeletal and Dermatological Sciences School of Biological Sciences The University of Manchester Manchester UK.
The Dermatology Centre Salford Royal Hospital Manchester Academic Health Science Centre The University of Manchester Manchester UK.
Skin Health Dis. 2024 Nov 19;4(6):e473. doi: 10.1002/ski2.473. eCollection 2024 Dec.
Sedentary behaviour has a detrimental effect on health independent of the amount of physical activity undertaken. Despite the association of cardiometabolic and psychosocial comorbidities with psoriasis, how physical behaviour influences health outcomes in patients with psoriasis is poorly understood.
We hypothesized that objective measurement of physical behaviour, using wearable digital technology, would have utility in understanding the clinical impact of an exercise intervention designed in partnership with patients with psoriasis.
Fourteen patients with psoriasis completed a 20-week study. During weeks 1-10, participants followed an incrementally progressive, exercise intervention, followed by independent activities during weeks 11-20. Accelerometers (GENEActiv Original) and pedometers recorded physical behaviour. Evaluation at week-0, -10, and -20 included assessment of psoriasis, cardiometabolic disease/risk, psychological health and functional capacity.
Our intervention supported significantly increased physical activity, including moderate-vigorous physical activity ( = 0.04) and step count ( = 0.04). We also observed a significant association between physical activity and psoriasis area and severity index (PASI)-50 response ( = 0.01) and psychosocial functioning ( = 0.029) together with a significant negative correlation between step count and psoriasis severity ( = 0.012). We observed no change in total waking hour sedentary behaviour.
Objective measurement of physical behaviour, using wearable digital technologies, offers a mechanism to further understand the clinical impact of lifestyle behaviour interventions. Crucially, despite increased levels of physical activity, we observed no change in total waking hour sedentary time. Further investigation is required to establish how modification of physical behaviour could offer an adjuvant management strategy for patients with psoriasis.
久坐行为对健康有不利影响，且独立于所进行的身体活动量。尽管心血管代谢和心理社会合并症与银屑病有关，但人们对身体行为如何影响银屑病患者的健康结局知之甚少。
我们假设，使用可穿戴数字技术对身体行为进行客观测量，将有助于理解与银屑病患者合作设计的运动干预的临床影响。
14名银屑病患者完成了一项为期20周的研究。在第1 - 10周，参与者遵循渐进性的运动干预，然后在第11 - 20周进行独立活动。加速度计（GENEActiv Original）和计步器记录身体行为。在第0、10和20周进行评估，包括对银屑病、心血管代谢疾病/风险、心理健康和功能能力的评估。
我们的干预显著增加了身体活动，包括中等强度到剧烈强度的身体活动（P = 0.04）和步数（P = 0.04）。我们还观察到身体活动与银屑病面积和严重程度指数（PASI）-50反应（P = 0.01）以及心理社会功能（P = 0.029）之间存在显著关联，同时步数与银屑病严重程度之间存在显著负相关（P = 0.012）。我们观察到清醒总时长的久坐行为没有变化。
使用可穿戴数字技术对身体行为进行客观测量，为进一步理解生活方式行为干预的临床影响提供了一种机制。至关重要的是，尽管身体活动水平有所提高，但我们观察到清醒总时长的久坐时间没有变化。需要进一步研究以确定改变身体行为如何能为银屑病患者提供辅助管理策略。
