Margolin G A, Zelentsov E V
Zh Vopr Neirokhir Im N N Burdenko. 1986 Jan-Feb(1):50-2.
The spinal epilepsy syndrome developed in 17 of 494 patients who were subjected to epidurography. Its cause was analysed in all cases. This syndrome develops evidently when a water-soluble iodine-containing contrast medium gains entry into the subarachnoid space or due to chance puncture of the dura mater during the manipulation or when the contrast medium flows through an opening in it which failed to close after a previous lumbar puncture. To prevent convulsions, epidurography should be conducted under careful control of the position of the needle in the epidural space and no earlier than 10 days after lumbar puncture. Because these rules were observed, none of the 216 epidurography procedures conducted since 1981 were complicated by spinal epilepsy.
494例行硬膜外造影的患者中有17例发生了脊髓癫痫综合征。对所有病例的病因进行了分析。当水溶性含碘造影剂进入蛛网膜下腔，或在操作过程中意外刺破硬脑膜，或造影剂通过先前腰椎穿刺后未能闭合的硬脑膜开口流出时，该综合征显然会发生。为预防惊厥，硬膜外造影应在仔细控制穿刺针在硬膜外间隙位置的情况下进行，且应在腰椎穿刺后不少于10天进行。由于遵守了这些规则，自1981年以来进行的216例硬膜外造影手术均未并发脊髓癫痫。
