河南眼压降低剂对有晶状体兔眼的眼内及视神经血流的影响。

Effect of honan intraocular pressure reducer on ocular and optic nerve blood flow in phakic rabbit eyes.

作者信息

Jay W M, Aziz M Z, Green K

出版信息

Acta Ophthalmol (Copenh). 1986 Feb;64(1):52-7. doi: 10.1111/j.1755-3768.1986.tb06871.x.

DOI:10.1111/j.1755-3768.1986.tb06871.x

Abstract

The Honan Intraocular Pressure Reducer (HIPR) was applied to rabbit eyes for 30 min at pressure settings of 0, 30, 50, or 100 mmHg. Ocular blood flow was measured using (85Sr) radioactively labelled 15 micron microspheres either with the HIPR applied to the eye or 15 min after removal. Intraocular pressure was measured before applying the HIPR, immediately after removal, or 15 min after removal. At all pressure settings, the HIPR significantly lowered the IOP (P less than or equal to 0.05) both immediately and 15 min after removal. At all pressure settings, except 0 mmHg, blood flow was significantly (P less than or equal to 0.05) both immediately and 15 min after removal. At all pressure settings, except 0 mmHg, blood flow was significantly (P less than or equal to 0.05) lower with the HIPR applied compared to 15 min after removal.

摘要

将河南眼压降低器（HIPR）以0、30、50或100 mmHg的压力设置应用于兔眼30分钟。使用（85Sr）放射性标记的15微米微球在应用HIPR于眼部时或移除后15分钟测量眼血流量。在应用HIPR之前、移除后立即或移除后15分钟测量眼压。在所有压力设置下，HIPR在移除后立即和15分钟时均显著降低眼压（P≤0.05）。在除0 mmHg外的所有压力设置下，移除后立即和15分钟时血流量均显著降低（P≤0.05）。在除0 mmHg外的所有压力设置下，与移除后15分钟相比，应用HIPR时血流量显著降低（P≤0.05）。