Ratemi Maryam, Gardner Matthew P H
Department of Psychology, Concordia University, Montreal, QC H4B 1R6, Canada.
Department of Psychology, Concordia University, Montreal, QC H4B 1R6, Canada.
Curr Biol. 2024 Dec 2;34(23):R1165-R1167. doi: 10.1016/j.cub.2024.10.060.
Hierarchical associations help animals navigate the environment by using contextual and latent states to guide learning and behavior. Chemogenetic inactivation in an occasion setting task reveals that orbitofrontal cortex is essential for implementing a hierarchical task structure, yet both orbitofrontal cortex and dorsal hippocampus are required for new learning based on the established task structure.
层级关联通过利用情境和潜在状态来指导学习与行为，帮助动物在环境中导航。在一个情境设置任务中进行化学遗传学失活研究发现，眶额叶皮质对于实施层级任务结构至关重要，然而基于既定任务结构的新学习既需要眶额叶皮质也需要背侧海马体。
