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一种与急性一氧化碳中毒后延迟出现的神经精神后遗症相关的脑综合征。

A brain syndrome associated with delayed neuropsychiatric sequelae following acute carbon monoxide intoxication.

作者信息

Min S K

出版信息

Acta Psychiatr Scand. 1986 Jan;73(1):80-6. doi: 10.1111/j.1600-0447.1986.tb02671.x.

DOI:10.1111/j.1600-0447.1986.tb02671.x
PMID:3962707
Abstract

A summary of clinical data is presented on 34 men and 52 women patients with brain syndrome associated with delayed neuropsychiatric sequelae following acute carbon monoxide intoxication. Their ages ranged from 34 to 82 years, with peak incidence in the sixth and seventh decade. Possible etiological factors were age, duration of unconsciousness on acute intoxication, and previous physical illness. The onset was relatively sudden after the apparent clear period which ranged from 2 to 40 days (mean 22.5 days). The most frequent symptoms were apathy, dull facial expressions, dementia, such as amnesia and disorientation, hypokinesia, mutism, irritable distractibility, urinary and/or fecal incontinence, gait disturbance and abnormal neurological signs and reflexes. EEG was abnormal in 33 of the 57 cases (58%). Of 27 patients who were given a computed tomographic brain scan, 15 patients were abnormal. The prognosis was relatively good in the follow-up study of 56 patients. Only age was related to a better prognosis.

摘要

本文呈现了34名男性和52名女性患者的临床数据总结,这些患者患有与急性一氧化碳中毒后延迟性神经精神后遗症相关的脑综合征。他们的年龄在34岁至82岁之间,发病高峰在第六和第七个十年。可能的病因包括年龄、急性中毒时的昏迷持续时间以及既往身体疾病。在明显的清醒期(2至40天,平均22.5天)后,发病相对突然。最常见的症状是冷漠、面部表情呆滞、痴呆,如失忆和定向障碍、运动减少、缄默、易激惹分心、尿失禁和/或大便失禁、步态障碍以及异常的神经体征和反射。57例中有33例(58%)脑电图异常。在接受脑部计算机断层扫描的27例患者中,15例异常。在对56例患者的随访研究中,预后相对较好。只有年龄与较好的预后相关。

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