Choi I S
Arch Neurol. 1983 Jul;40(7):433-5. doi: 10.1001/archneur.1983.04050070063016.
Of 2,360 victims of acute carbon monoxide intoxication examined between 1976 and 1981, delayed neurologic sequelae were diagnosed in 65 (2.75% of the total group, 11.8% of those admitted). There were 25 men and 40 women. Ages ranged from 34 to 80 years (mean, 56.1 years), with the peak incidence in the sixth and seventh decades. The lucid interval before appearance of neurologic sequelae varied from two to 40 days (mean, 22.4 days). The most frequent symptoms were mental deterioration, urinary or fecal incontinence, gait disturbance, and mutism; the most frequent signs were masked face, glabella sign, grasp reflex, increased muscle tone, short-step gait, and retropulsion. There were no important contributory factors except age and the severity of anoxia. Previous associated disease did not hasten the development of sequelae. Of 36 patients followed up for two years, 27 (75%) recovered within one year.
在1976年至1981年间检查的2360例急性一氧化碳中毒受害者中，65例被诊断为有迟发性神经后遗症（占总病例组的2.75%，占入院患者的11.8%）。其中男性25例，女性40例。年龄范围为34至80岁（平均56.1岁），发病高峰在第六和第七个十年。神经后遗症出现前的清醒期从2天到40天不等（平均22.4天）。最常见的症状是精神衰退、大小便失禁、步态障碍和缄默症；最常见的体征是面具脸、眉间征、抓握反射、肌张力增加、短步幅步态和后冲。除年龄和缺氧严重程度外，没有其他重要的促成因素。既往相关疾病并未加速后遗症的发展。在36例随访两年的患者中，27例（75%）在一年内康复。
