Uchida T, Kobayashi K, Honda N, Omata T, Ao T, Odajima K, Mashimo S, Endo T, Ishibashi A, Koshiba K
Hinyokika Kiyo. 1986 Jan;32(1):19-26.
Twenty-two cases of primary ureteral tumors treated at our Department between July 1971 and December 1984, were reviewed. The patients ranged from 28 to 83 years old (average 63.6 years). There were 17 males and 5 females (3.4:1). The affected side was predominantly the left (15) than the right (7). The most common site of the tumor growth was at the lower third of the ureter (14 cases, 63.6%). The most common initial symptom was macroscopic hematuria, which was seen in 17 cases (77.3%). The major finding of IVP was non-visualizing kidney in 11 cases (50.0%) and filling defect in 7 cases (31.8%). Positive urinary cytology was obtained in 9 cases (52.9%) by voided urine and 6 cases (66.6%) by catheterized urine. Total nephroureterectomy associated with partial cystectomy was performed in 14 cases (63.6%). Histologically, 19 cases were transitional cell carcinoma (86.8%). Associated growth of urothelial tumor in the bladder was found in 4 cases preoperatively and in 3 cases during the course of postoperative follow up. All of them were treated by transurethral resection. Overall survival rate at 1,2,3,4 and 5 years was 84, 71, 55, 46 and 35%, respectively, by the Kaplan-Meier method. The five year survival rate was 54% for the low stage group and 0% for the high stage group; 54% for the low grade group and 26% for the high grade group. (p value = not significant, generalized Wilcoxon test).
回顾了1971年7月至1984年12月间在我科治疗的22例原发性输尿管肿瘤病例。患者年龄在28岁至83岁之间（平均63.6岁）。男性17例，女性5例（3.4:1）。患侧以左侧（15例）为主，多于右侧（7例）。肿瘤生长最常见的部位是输尿管下三分之一处（14例，63.6%）。最常见的首发症状是肉眼血尿，17例（77.3%）出现此症状。静脉肾盂造影（IVP）的主要表现为11例（50.0%）患肾不显影，7例（31.8%）有充盈缺损。通过自行排尿获得阳性尿细胞学检查结果的有9例（52.9%），通过导尿获得阳性结果的有6例（66.6%）。14例（63.6%）患者接受了全肾输尿管切除术并联合部分膀胱切除术。组织学检查显示，19例为移行细胞癌（86.8%）。术前发现4例膀胱内有尿路上皮肿瘤伴发生长，术后随访过程中又发现3例。所有这些病例均接受经尿道切除术治疗。采用Kaplan-Meier法计算，1年、2年、3年、4年和5年的总生存率分别为84%、71%、55%、46%和35%。低分期组5年生存率为54%，高分期组为0%；低级别组为54%，高级别组为26%。（p值=无显著性差异，广义Wilcoxon检验）
