Podvinec M, Rufli T, Sopko J, Wey W
HNO. 1979 Sep;27(9):292-7.
The early clinical and histological diagnosis of acquired bullous dermatoses (pemphigus, bullous pemphigoid and the cicatricical pemphigoid of mucous membranes) may prove to be difficult when the disease is confined to the upper air and food passages. Histological differentiation between these diseases can also be difficult. In a number of cases it could be shown that the first signs of the disease were frequently mistaken for inflammatory conditions and that routine histological examination rarely confirmed the diagnosis. Only after immunohistological and immunoserological examination could the diagnosis be confirmed. In pemphigus, the treatment can be individually adapted to the titre of antibodies. The typical otorhinolaryngological findings in each of the three diseases are described.
当获得性大疱性皮肤病(天疱疮、大疱性类天疱疮和黏膜瘢痕性类天疱疮)局限于上呼吸道和消化道时,早期临床和组织学诊断可能会很困难。这些疾病之间的组织学鉴别也可能存在困难。在许多病例中,可以发现疾病的最初迹象常常被误诊为炎症性疾病,常规组织学检查很少能确诊。只有经过免疫组织学和免疫血清学检查才能确诊。在天疱疮中,治疗可根据抗体滴度进行个体化调整。文中描述了这三种疾病各自典型的耳鼻喉科表现。