Li Mengwan, Liu Dan, Han Tingting, Li Juan, Chen Linbo, Li Daxiang, Xie Zhongwen
State Key Laboratory of Tea Plant Biology and Utilization, School of Tea and Food Sciences and Technology, Anhui Agricultural University, Hefei, Anhui 230036, PR China.
Joint Research Center for Food Nutrition and Health of IHM, Anhui Agricultural University, Hefei, Anhui 230036, PR China.
Food Chem X. 2024 Nov 9;24:101989. doi: 10.1016/j.fochx.2024.101989. eCollection 2024 Dec 30.
Dali tea (DLT) made by wild tea plant ( has been very popular in the market。However, the signature compounds and health benefits of DLT were not reported yet. To comprehensively understand metabolite signatures and potential health-function, the distinct metabolite signatures and hypoadiposity effect between DLT and Yunkang tea (YKT, made by Yunkang 10) were comparative investigated. Our data found that catechins, and dimeric catechins were lower in DLT than YKT. In contrast, the levels of phenolic acid and amino acids were higher in DLT than YKT. An un-targeted metabolomics and a chemometric analysis indicated that flavonoid biosynthesis is a major pathway that distinguishes DLT from YKT. Additionally, chlorogenic acid, ellagic acid, arginine, tyrosine, and theanine were identified as characteristic metabolites of DLT. Furthermore, animal experiment showed that YKT performs better efficiency than DLT on alleviating hyperadiposity and renal damages in high-fat-diet induced obese mice.
由野生茶树制成的大理茶（DLT）在市场上一直很受欢迎。然而，DLT的标志性化合物和健康益处尚未见报道。为全面了解代谢物特征和潜在健康功能，对DLT与云抗茶（YKT，由云抗10制成）之间不同的代谢物特征和减肥效果进行了比较研究。我们的数据发现，DLT中的儿茶素和二聚体儿茶素含量低于YKT。相反，DLT中酚酸和氨基酸的含量高于YKT。非靶向代谢组学和化学计量分析表明，类黄酮生物合成是区分DLT和YKT的主要途径。此外，绿原酸、鞣花酸、精氨酸、酪氨酸和茶氨酸被鉴定为DLT的特征性代谢物。此外，动物实验表明，在缓解高脂饮食诱导的肥胖小鼠的肥胖和肾损伤方面，YKT比DLT表现出更好的效果。
