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产后可逆性脑血管收缩综合征并发脑出血:一例报告

Intracerebral hemorrhage as a complication of reversible cerebral vasoconstriction syndrome in the postpartum periods: a case report.

作者信息

Puti Nazla Ananda Rachmi, Sani Achmad Firdaus, Kurniawan Dedy

机构信息

Department of Neurology, Faculty of Medicine, Universitas Airlangga, Soetomo Academic General Hospital, Surabaya, Indonesia.

出版信息

Pan Afr Med J. 2024 Aug 8;48:164. doi: 10.11604/pamj.2024.48.164.44737. eCollection 2024.

Abstract

Reversible cerebral vasoconstriction syndrome (RCVS) is a cerebrovascular condition marked by the diffuse, reversible narrowing of multiple segments of cerebral arteries. This syndrome predominantly affects women and most commonly presents around the age of 42. It can develop spontaneously or be induced by factors such as the postpartum period or exposure to vasoactive substances. This case report describes an uncommon presentation of RCVS in a 24-year-old woman who developed an intraparenchymal hemorrhage shortly after a spontaneous vaginal delivery, despite the absence of conventional stroke risk factors. Diagnostic imaging with digital subtraction angiography (DSA) revealed multifocal vasoconstriction in the right and left anterior and middle cerebral arteries, along with the vertebrobasilar system, an indication of RCVS. Notably, vasoconstriction improved following intra-arterial nimodipine administration. This case underscores the importance of considering RCVS in postpartum women presenting with headaches and neurological deficits, as timely magnetic resonance imaging, computed tomography (CT) angiography, or brain angiography is critical for accurate diagnosis and optimal management, ultimately reducing the risk of poor prognosis.

摘要

可逆性脑血管收缩综合征(RCVS)是一种脑血管疾病,其特征为脑动脉多个节段的弥漫性、可逆性狭窄。该综合征主要影响女性,最常见于42岁左右发病。它可自发出现,也可由产后或接触血管活性物质等因素诱发。本病例报告描述了一名24岁女性中RCVS的罕见表现,该女性在自然阴道分娩后不久发生脑实质内出血,尽管没有传统的中风危险因素。数字减影血管造影(DSA)诊断成像显示右侧和左侧大脑前动脉及中动脉以及椎基底系统存在多灶性血管收缩,这是RCVS的表现。值得注意的是,动脉内给予尼莫地平后血管收缩情况有所改善。本病例强调了对于出现头痛和神经功能缺损的产后女性考虑RCVS的重要性,因为及时进行磁共振成像、计算机断层扫描(CT)血管造影或脑血管造影对于准确诊断和最佳治疗至关重要,最终可降低预后不良的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ceee/11614112/8a3adf1e4376/PAMJ-48-164-g001.jpg

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