Krishna Goutham, Manuel Shilpa M, Ananthakrishnan V M
Department of General Medicine, Government Medical College, Kozhikode, Kerala, India.
J Family Med Prim Care. 2024 Oct;13(10):4727-4729. doi: 10.4103/jfmpc.jfmpc_1826_23. Epub 2024 Oct 18.
Eosinophilia can be due to both infectious and non-infectious causes, many of which may be clinically indistinguishable. Filariasis, a tropical and subtropical infection, is caused by Wuchereria bancrofti, Brugia timori (B. timori), and Brugia malayi. Filariasis is conventionally diagnosed by demonstration of microfilaria in the peripheral blood smear. The disease may be missed if one is not aware of the possibility. We report two cases in two individuals with eosinophilia due to filaria resulting in tropical pulmonary eosinophilia and deep vein thrombosis (DVT). They had complete symptomatic improvement after a 3-week course of diethylcarbamazine (DEC) +/- ivermectin.
嗜酸性粒细胞增多可由感染性和非感染性原因引起,其中许多在临床上可能难以区分。丝虫病是一种热带和亚热带感染,由班氏吴策线虫、帝汶布鲁线虫和马来布鲁线虫引起。丝虫病传统上通过在外周血涂片中发现微丝蚴来诊断。如果不了解这种可能性,该病可能会被漏诊。我们报告了两例因丝虫病导致嗜酸性粒细胞增多,进而引发热带肺嗜酸性粒细胞增多症和深静脉血栓形成(DVT)的病例。在接受为期3周的乙胺嗪(DEC)+/-伊维菌素治疗后,他们的症状完全改善。