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口腔健康出生队列研究的国际研究议程。

An International Research Agenda for Oral Health Birth Cohort Studies.

作者信息

Peres K G, Kalhan A C, Sarawagi S, Peres M A, Feldens C A, Chaffee B W, Barros A J D, Rugg-Gunn A, Nascimento G G

机构信息

National Dental Research Institute Singapore, National Dental Centre Singapore, Singapore.

Oral Health ACP, Health Services and Systems Research Programme, Duke-NUS Medical School, Singapore.

出版信息

J Dent Res. 2025 Feb;104(2):147-154. doi: 10.1177/00220345241286869. Epub 2024 Dec 4.

Abstract

The GLOBICS-Global Consortium of Oral Health Birth Cohort Studies (OHBCS)-is a long-lasting international collaborative research group among existing OHBCS, established in response to the Lancet Series on Oral Health, which pointed out the need to shift the global oral health agenda. This study aimed to identify priority research questions from OHBCS that can be leveraged to improve children's global oral health. A 2-phase online Delphi process sought consensus over research priorities for OHBCS. Participants were identified by mapping existing OHBCS. Fourteen research questions were grouped into 4 thematic areas. A 9-point Likert-type scale was applied. Consensus was achieved if the question had (1) at least 51% of participants scoring a research question as "high priority," (2) an interquartile range of <2.5, and (3) a standard deviation of <1.7 or 75% of responses falling between 2 points above and below the mean score. Forty-four of 114 participants completed the Delphi survey. The 8 research priorities identified included questions about the effect of childhood dental visits on oral health throughout life ( = 2), questions related to sugar consumption and dental caries in childhood and adolescence ( = 4), infant growth and dental diseases ( = 1), and whether socioeconomic inequalities in dental caries are mitigated by fluoride exposure ( = 1). Guided by expert insight, the priorities identified for future OHBCS research should leverage a life course perspective to address knowledge gaps in children's oral health and oral health equity.

摘要

全球口腔健康出生队列研究联盟(GLOBICS - Global Consortium of Oral Health Birth Cohort Studies,简称OHBCS)是一个由现有口腔健康出生队列研究组成的长期国际合作研究小组,它是为响应《柳叶刀》关于口腔健康的系列文章而成立的,该系列文章指出有必要转变全球口腔健康议程。本研究旨在确定口腔健康出生队列研究中的优先研究问题,这些问题可用于改善全球儿童口腔健康。通过两阶段在线德尔菲法就口腔健康出生队列研究的研究重点达成共识。通过梳理现有的口腔健康出生队列研究来确定参与者。将14个研究问题分为4个主题领域。采用9点李克特量表。如果问题满足以下条件则达成共识:(1)至少51%的参与者将某个研究问题评为“高优先级”;(2)四分位间距小于2.5;(3)标准差小于1.7,或75%的回答落在平均分上下2分之间。114名参与者中有44人完成了德尔菲调查。确定的8个研究重点包括关于儿童期看牙对一生口腔健康的影响(=2)、与儿童和青少年时期糖摄入及龋齿相关的问题(=4)、婴儿生长与牙齿疾病(=1)以及龋齿方面的社会经济不平等是否因氟暴露而减轻(=1)。在专家见解的指导下,为未来口腔健康出生队列研究确定的重点应利用生命历程视角来填补儿童口腔健康和口腔健康公平方面的知识空白。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e50/11752651/bdf71456bf1c/10.1177_00220345241286869-fig1.jpg

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