巴西炎性肠病患者样本中的性别差异。
Sex differences in a Brazilian sample of patients with inflammatory bowel disease.
作者信息
Pascholatto Khadija Assis, Santos Laura Ribeiro, Skare Thelma Larocca, Ramos Júnior Odery, Nisihara Renato
机构信息
Mackenzie Evangelical School of Medicine of Paraná - Curitiba (PR), Brazil.
Universidade Federal do Paraná, Department of Clinical Medicine - Curitiba (PR), Brazil.
出版信息
Rev Assoc Med Bras (1992). 2024 Dec 2;70(12):e20240963. doi: 10.1590/1806-9282.20240963. eCollection 2024.
BACKGROUND
Inflammatory bowel diseases such as Crohn's disease and ulcerative colitis are influenced by environmental and immunological factors and may differ according to the patient's sex.
OBJECTIVE
The objective was to study the differences in the clinical profile of a Brazilian sample of inflammatory bowel disease patients according to sex.
METHODS
Retrospective study with chart review of 158 inflammatory bowel disease patients (43 with Crohn's disease and 115 with ulcerative colitis) from a single university hospital in southern Brazil.
RESULTS
The Crohn's disease sample showed a female/male ratio of 2.1, and the sample of ulcerative colitis showed a ratio of 1.5. The only significant difference found in the clinical profile was an increased constipation rate in female patients with ulcerative colitis. No other differences in epidemiological, symptom profile, or treatment could be detected.
CONCLUSIONS
More females with inflammatory bowel diseases sought healthcare facilities compared to males. The only notable difference was a higher incidence of constipation symptoms among females; all other aspects were similar between the sexes.
背景
克罗恩病和溃疡性结肠炎等炎症性肠病受环境和免疫因素影响，且可能因患者性别而异。
目的
研究巴西炎症性肠病患者样本在临床特征上的性别差异。
方法
对巴西南部一家大学医院的158例炎症性肠病患者（43例克罗恩病患者和115例溃疡性结肠炎患者）进行回顾性研究并查阅病历。
结果
克罗恩病样本的女性/男性比例为2.1，溃疡性结肠炎样本的该比例为1.5。在临床特征方面发现的唯一显著差异是溃疡性结肠炎女性患者的便秘发生率增加。在流行病学、症状特征或治疗方面未发现其他差异。
结论
与男性相比，更多患有炎症性肠病的女性寻求医疗保健机构的帮助。唯一显著的差异是女性便秘症状的发生率较高；两性之间的所有其他方面相似。
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