巴西炎症性肠病患者样本中皮肤损伤的患病率。
Prevalence of skin lesions in a sample of Brazilian patients with inflammatory bowel disease.
机构信息
Mackenzie Evangelical School of Medicine - Curitiba (PR), Brazil.
Universidade Positivo, Departmento de Medicina - Curitiba (PR), Brazil.
出版信息
Rev Assoc Med Bras (1992). 2023 Aug 14;69(8):e20230165. doi: 10.1590/1806-9282.20230165. eCollection 2023.
OBJECTIVE
Inflammatory bowel diseases may have extra intestinal manifestations such as those affecting the skin. This study aimed to study skin manifestations in a cohort of Brazilian patients with inflammatory bowel diseases.
METHODS
Epidemiological and clinical data were obtained through a cross-sectional study of 70 inflammatory bowel diseases patients and a control group comprising 50 healthy individuals. All patients were subjected to dermatological examination and photography of skin lesions.
RESULTS
Out of the 70 inflammatory bowel diseases patients, 50 had ulcerative colitis and 20 had Crohn's disease. Skin lesions occurred in 95.7% of the inflammatory bowel diseases patients and in 88% of individuals in the control group (p=0.001). Alopecia (p<0.0001), xerosis (p=0.03), striae (p=0.02), and acne (p=0.04) were more common in inflammatory bowel diseases patients than in the control group. Alopecia was more frequent in females (p=0.01) than in males. Two male patients, one with ulcerative colitis and the other with Crohn's disease, had pyoderma gangrenosum. Erythema nodosum was not observed in both groups.
CONCLUSION
There was a high prevalence of skin lesions in the Brazilian inflammatory bowel diseases patients. Additionally, alopecia, xerosis, striae, and acne were more common in patients with inflammatory bowel diseases than in those in the control group.
目的
炎症性肠病可能有肠外表现，如影响皮肤的表现。本研究旨在研究巴西炎症性肠病患者队列中的皮肤表现。
方法
通过对 70 例炎症性肠病患者和 50 名健康对照者进行横断面研究，获得流行病学和临床数据。所有患者均接受皮肤科检查和皮肤损伤摄影。
结果
在 70 例炎症性肠病患者中，50 例为溃疡性结肠炎，20 例为克罗恩病。炎症性肠病患者中有 95.7%出现皮肤损伤，对照组中有 88%（p=0.001）。炎症性肠病患者比对照组更常见脱发（p<0.0001）、干燥（p=0.03）、条纹（p=0.02）和痤疮（p=0.04）。脱发在女性中更为常见（p=0.01），而非男性。两名男性患者，一名患有溃疡性结肠炎，另一名患有克罗恩病，患有坏疽性脓皮病。两组均未观察到结节性红斑。
结论
巴西炎症性肠病患者皮肤损伤的患病率较高。此外，脱发、干燥、条纹和痤疮在炎症性肠病患者中比对照组更为常见。
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