Lattermann Christian
Harvard University.
Arthroscopy. 2025 Jul;41(7):2666-2667. doi: 10.1016/j.arthro.2024.11.085. Epub 2024 Dec 2.
Anterior cruciate ligament (ACL) injuries do not heal anatomically on their own and often lead to post-traumatic osteoarthritis (PTOA). ACL reconstruction, though effective, can contribute to PTOA, and donor site morbidity remains a concern with autografts. While ACL repair has traditionally shown poorer outcomes (27% failure rate in the 1990s and early 2000s), a recent review of newer techniques shows promising results and no significant differences in patient-reported outcomes between repair and reconstruction. Today's repair and augmentation methods are more advanced than those used 20 to 30 years ago; technologies like bridge-enhanced ACL repair and dynamic intraligamentary stabilization appear more promising than simple suture augmentation. Biological concerns, particularly the inability of the ACL to mount a healing response due to the rupture of its synovial envelope, have been addressed most effectively by the bridge-enhanced ACL repair method, with studies showing promising results in animal models and human trials. A better understanding of tear patterns and ACL bundle anatomy has also enhanced our ability to identify suitable candidates for repair. ACL repair techniques could help reduce the inflammatory response that accelerates PTOA after ACL injury and surgery. This makes repair a potentially attractive option for certain patients, particularly older or less active individuals who may not need a traditional ACL reconstruction. Still, caution is required. I believe young, active athletes should still be treated with traditional autograft reconstruction, as repair techniques have not yet proven superior in this group, with failure rates of 20% to 30%.
前交叉韧带(ACL)损伤无法自行实现解剖学愈合,且常导致创伤后骨关节炎(PTOA)。ACL重建虽有效果,但也可能引发PTOA,并且自体移植时供体部位的并发症仍是一个问题。传统上,ACL修复的效果较差(在20世纪90年代和21世纪初失败率为27%),但最近对新技术的综述显示出了有前景的结果,且修复和重建在患者报告的结果方面没有显著差异。如今的修复和增强方法比20到30年前使用的方法更先进;像桥接增强ACL修复和动态韧带内稳定等技术似乎比简单的缝线增强更有前景。生物学方面的问题,尤其是由于ACL滑膜包膜破裂而无法产生愈合反应,已通过桥接增强ACL修复方法得到了最有效的解决,研究表明在动物模型和人体试验中都有有前景的结果。对撕裂模式和ACL束解剖结构的更好理解也提高了我们识别适合修复的候选者的能力。ACL修复技术有助于减少ACL损伤和手术后加速PTOA的炎症反应。这使得修复对于某些患者,特别是可能不需要传统ACL重建的老年人或活动较少的个体来说是一个潜在有吸引力的选择。不过,仍需谨慎。我认为年轻、活跃的运动员仍应接受传统的自体移植重建治疗,因为修复技术在这一群体中尚未被证明更优越,失败率为20%至30%。