Chen Lu, He Xige, Han Yunfei, Huang Yajuan, Li Jin, Li Jin, Yu Xueting, Yun Xueyan, Wu Jindi, Sha Rina, Dong Tungalag, Borjigin Gerelt
College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010018, China.
College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010018, China; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot 010020, China.
Food Chem. 2025 Mar 1;467:142243. doi: 10.1016/j.foodchem.2024.142243. Epub 2024 Nov 26.
The objective of this study was to optimize the utilization of deposited fat in Sunit sheep, with a focus on dietary nutrition. This study also elucidated variations in lipid metabolism among subcutaneous fat (SF), perirenal fat (PF), and tail fat (TF) in sheep of different ages using non-targeted lipidomic techniques. In total, 173 different lipids were identified, of which triacylglycerol (TG) and phosphatidylcholine (PC) were prominent. The relative intensity of TG was highest at 6 months of age in three adipose depots. Glycerophospholipids (PLs) were expressed at peak levels in TF and SF at 18 months of age. Pathway analysis revealed that biosynthesis of unsaturated fatty acids, linoleic acid metabolism, glycerophospholipid metabolism, and fatty acid biosynthesis were the main pathways involved in the metabolism of adipose depots. These findings provide a comprehensive reference for the metabolic characteristics and pathways of adipose tissue in sheep and the utilization of its by-products.
本研究的目的是优化苏尼特羊沉积脂肪的利用，重点关注日粮营养。本研究还使用非靶向脂质组学技术阐明了不同年龄绵羊皮下脂肪（SF）、肾周脂肪（PF）和尾脂（TF）之间脂质代谢的差异。总共鉴定出173种不同的脂质，其中三酰甘油（TG）和磷脂酰胆碱（PC）最为突出。在三个脂肪库中，TG的相对强度在6月龄时最高。甘油磷脂（PLs）在18月龄时在TF和SF中表达达到峰值。通路分析表明，不饱和脂肪酸的生物合成、亚油酸代谢、甘油磷脂代谢和脂肪酸生物合成是参与脂肪库代谢的主要途径。这些发现为绵羊脂肪组织的代谢特征和途径及其副产品的利用提供了全面的参考。
