To err is human … so how can we prevent all ABO-incompatible transfusions?

Savin et al. report a retrospective analysis of ABO-incompatible red cell transfusions in the United Kingdom, France and Germany. In spite of varied strategies for bedside preventative measures, all three countries continue to identify preventable errors leading to ABO-incompatible red cell transfusions. This report highlights the ongoing challenge of human error as a factor in the persistence of preventable mistransfusions. Commentary on: Savin et al. Frequencies and causes of ABO-incompatible red cell transfusions in France, Germany and the United Kingdom. Br J Haematol 2025; 206:726-734.