Chow W H, Daling J R, Weiss N S, Moore D E, Soderstrom R M, Metch B J
Am J Public Health. 1986 May;76(5):536-9. doi: 10.2105/ajph.76.5.536.
As part of a case-control study of tubal ectopic pregnancy (TEP), we sought to evaluate the possible etiologic role of use of an intrauterine device (IUD) prior to conception. We interviewed 155 women who had a tubal ectopic pregnancy treated at one of five Seattle, Washington hospitals between 1975-79 regarding their reproductive, contraceptive, and medical histories; 456 women who delivered a baby in King County during the same period were identified from vital records and interviewed as controls. An elevated risk of TEP was detected among former users of the Dalkon Shield (adjusted OR = 2.5; 95% CI = 1.3-4.7). Women who had used other IUDs did not have an excess risk of TEP.
作为输卵管异位妊娠(TEP)病例对照研究的一部分,我们试图评估受孕前使用宫内节育器(IUD)可能的病因作用。我们采访了1975年至1979年间在华盛顿州西雅图市五家医院之一接受输卵管异位妊娠治疗的155名女性,了解她们的生殖、避孕和病史;从生命记录中识别出同期在金县分娩的456名女性作为对照并进行采访。在曾使用过Dalkon Shield节育器的女性中检测到TEP风险升高(校正比值比=2.5;95%置信区间=1.3-4.7)。使用过其他宫内节育器的女性没有TEP额外风险。