Haghighat Mohsen, Darcie Thomas, Smith Levi
Department of Electrical and Computer Engineering, University of Victoria, Victoria, BC, V8P 5C2, Canada.
Centre for Advanced Materials and Related Technology (CAMTEC), University of Victoria, Victoria, BC, V8W 2Y2, Canada.
Sci Rep. 2024 Dec 5;14(1):30279. doi: 10.1038/s41598-024-81731-1.
This paper demonstrates an on-chip anhydrous D-glucose sensor using a coplanar stripline (CPS) on a thin (1 [Formula: see text]m) silicon nitride membrane at terahertz (THz) frequencies. A thin layer (≈ 10 [Formula: see text]m) of D-glucose was placed in close proximity to the CPS and the transmission response was measured using a modified THz-TDS setup. The D-glucose introduces frequency-dependent changes to the effective permittivity of the CPS resulting in a modified spectral response at the receiver. Measurement results show absorption signatures at 1.42 THz and 2.07 THz corresponding to the first two significant resonances beyond 1 THz for D-glucose allowing for label-free detection. The frequency-dependent attenuation coefficient was estimated by simulation for several D-glucose layer thicknesses using a modified Lorentz model. Measurement results align with simulations and other literature that use free-space THz radiation. This work verifies on-chip THz sensing of D-glucose and presents a pathway toward on-chip sensing of other materials at THz frequencies.
本文展示了一种片上无水 D - 葡萄糖传感器，它在太赫兹（THz）频率下，利用位于薄（1μm）氮化硅膜上的共面带状线（CPS）制成。将一层薄的（≈10μm）D - 葡萄糖放置在靠近 CPS 的位置，并使用改进的太赫兹时域光谱（THz - TDS）装置测量传输响应。D - 葡萄糖会使 CPS 的有效介电常数发生频率依赖性变化，从而在接收器处产生修改后的光谱响应。测量结果显示，在 1.42 THz 和 2.07 THz 处有吸收特征，这对应于 D - 葡萄糖在 1 THz 以上的前两个显著共振，实现了无标记检测。使用改进的洛伦兹模型，通过模拟几种 D - 葡萄糖层厚度，估算了频率依赖性衰减系数。测量结果与使用自由空间太赫兹辐射的模拟结果及其他文献相符。这项工作验证了片上太赫兹对 D - 葡萄糖的传感，并为太赫兹频率下片上对其他材料的传感提供了一条途径。
