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Bone-independent extramedullary disease is associated with inferior overall survival in multiple myeloma patients: a single-center, real-world experience.

作者信息

Xu Ke, Agbuduwe Charles, Kanellias Nickolaos, Wilson William, McMillan Annabel, Papanikolaou Xenofon, Lee Lydia, Popat Rakesh, Sive Jonathan, Rabin Neil, Yong Kwee, Parcharidou Agapi, Kyriakou Charalampia

机构信息

University College London Hospitals NHS Trust, London.

London North West University Healthcare NHS Trust, London.

出版信息

Haematologica. 2025 May 1;110(5):1182-1186. doi: 10.3324/haematol.2024.286409. Epub 2024 Dec 5.

DOI:10.3324/haematol.2024.286409
PMID:39633554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12050924/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/219d/12050924/e2f9149d658f/1101182.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/219d/12050924/e2f9149d658f/1101182.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/219d/12050924/e2f9149d658f/1101182.fig1.jpg

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N Engl J Med. 2023 Sep 14;389(11):1009-1022. doi: 10.1056/NEJMoa2303194. Epub 2023 Aug 30.
2
Clinical characteristics and outcomes of IgD myeloma: experience across UK national trials.IgD 骨髓瘤的临床特征和结局:英国国家试验中的经验。
Blood Adv. 2022 Sep 13;6(17):5113-5123. doi: 10.1182/bloodadvances.2022007608.
3
Treatment Options for Patients With Heavily Pretreated Relapsed and Refractory Multiple Myeloma.
多次接受治疗的复发难治性多发性骨髓瘤患者的治疗选择
Clin Lymphoma Myeloma Leuk. 2022 Jul;22(7):460-473. doi: 10.1016/j.clml.2022.01.011. Epub 2022 Jan 19.
4
Multiple Extramedullary-Bone Related and/or Extramedullary Extraosseous Are Independent Poor Prognostic Factors in Patients With Newly Diagnosed Multiple Myeloma.多部位髓外骨相关和/或髓外骨外病变是新诊断多发性骨髓瘤患者独立的不良预后因素。
Front Oncol. 2021 Jul 7;11:668099. doi: 10.3389/fonc.2021.668099. eCollection 2021.
5
Multiple myeloma.多发性骨髓瘤。
Lancet. 2021 Jan 30;397(10272):410-427. doi: 10.1016/S0140-6736(21)00135-5.
6
Melflufen plus dexamethasone in relapsed and refractory multiple myeloma (O-12-M1): a multicentre, international, open-label, phase 1-2 study.美法仑氟芬酰胺联合地塞米松治疗复发难治性多发性骨髓瘤(O-12-M1):一项多中心、国际性、开放标签的1/2期研究
Lancet Haematol. 2020 May;7(5):e395-e407. doi: 10.1016/S2352-3026(20)30044-2. Epub 2020 Mar 23.
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Outcome of paraosseous extra-medullary disease in newly diagnosed multiple myeloma patients treated with new drugs.新诊断多发性骨髓瘤患者新药物治疗后骨旁髓外疾病的结果。
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