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应对急性中风的全身性并发症:美国心脏协会的科学声明

Addressing Systemic Complications of Acute Stroke: A Scientific Statement From the American Heart Association.

作者信息

Kumar Sandeep, Chou Sherry H-Y, Smith Craig J, Nallaparaju Anusha, Laurido-Soto Osvaldo Jose, Leonard Anne D, Singla Ajay K, Leonhardt-Caprio Ann, Stein Daniel Joseph

出版信息

Stroke. 2025 Jan;56(1):e15-e29. doi: 10.1161/STR.0000000000000477. Epub 2024 Dec 5.

DOI:10.1161/STR.0000000000000477
PMID:39633600
Abstract

Systemic, nonneurological complications are common after ischemic and hemorrhagic strokes, affect different organ systems, and have a major impact on patient outcomes. Despite their obvious implications, this area in stroke management remains inadequately researched, and current literature offers fragmentary guidance for care. The purpose of this scientific statement is to elucidate the major systemic complications of strokes that occur during hospitalization, to synthesize evidence from current literature and existing guidelines, to address gaps in knowledge, and to provide a coherent set of suggestions for clinical care based on interpretation of existing evidence and expert opinion. This document advocates for improved interdisciplinary collaboration, team effort, and effective implementation strategies to reduce the burden of these events in clinical practice. It also calls for further research on strategies for preventing and managing systemic complications after stroke that improve outcomes in stroke survivors.

摘要

缺血性和出血性中风后,全身性非神经并发症很常见,会影响不同的器官系统,并对患者的预后产生重大影响。尽管其影响明显,但中风管理的这一领域仍研究不足,当前文献提供的护理指导也支离破碎。本科学声明的目的是阐明住院期间发生的中风的主要全身性并发症,综合当前文献和现有指南中的证据,填补知识空白,并根据现有证据的解读和专家意见,提供一套连贯的临床护理建议。本文倡导加强跨学科协作、团队合作以及有效的实施策略,以减轻这些事件在临床实践中的负担。它还呼吁进一步研究预防和管理中风后全身性并发症的策略,以改善中风幸存者的预后。

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引用本文的文献

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Pulmonary Embolism in Acute Ischaemic Stroke: Evolving Evidence, Diagnostic Challenges, and a Novel Thromboinflammatory Axis Hypothesis.急性缺血性卒中中的肺栓塞:不断发展的证据、诊断挑战及一种新的血栓炎症轴假说
Int J Mol Sci. 2025 Jul 14;26(14):6733. doi: 10.3390/ijms26146733.
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Associations of Estimated Glucose Disposal Rate With Stroke Risk and Poststroke Adverse Outcomes: A Prospective Cohort Study.估计葡萄糖处置率与中风风险及中风后不良结局的关联:一项前瞻性队列研究。
CNS Neurosci Ther. 2025 Jun;31(6):e70420. doi: 10.1111/cns.70420.