Yin Yangyan, Peng Hao, Bai Huili, Pei Zhe, Chen Zhongwei, Ma Chunxia, Zhu Min, Li Jun, Li Changting, Gong Yu, Wang Leping, Teng Ling, Qin Zhongsheng, Zhou Jianhui, Wei Tianchao, Liao Yuying
Institute of Animal Science and Technology, Guangxi University, Nanning, China.
Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning, China.
Front Microbiol. 2024 Nov 20;15:1450690. doi: 10.3389/fmicb.2024.1450690. eCollection 2024.
strains are potentially rich sources of probiotics that could help avoid infections. In order to evaluate their efficacy in bolstering resistance to infection among chicks. In this study, and commercial probiotics were administered via the water supply at a dosage of 1×10 CFU per chicken from days 1 to 7 to establish a protective system for the chicks. On days 8 and 9, was attacked to investigate the preventive effects and potential mechanisms of in comparison with commercial probiotics. Post-treatment, we took a broad range of measurements, including body weight, immune organ index changes, the viable count of in the liver, spleen, and cecum, as well as pathological changes in the liver. Our findings demonstrated that both and the commercial probiotic could safeguard chicks from infection. The data also suggested that probiotic medication could ease weight loss postinfection, lower the bacterial count in the liver, spleen, and cecum, and attenuate liver pathological damage among all treated participants. Subsequently, we did high-throughput sequencing of 16S rRNA to examine the fecal microbiota of the chicks 5 days post-infection. We discovered that both and the commercial probiotic could fend off the invasion of by affecting the bacterial population of , and . Generally speaking, the addition of as a feed additive protects yellow-feathered broilers from illness, suggesting great potential for commercial uses in the poultry industry.
菌株是潜在的丰富益生菌来源,有助于避免感染。为了评估它们在增强雏鸡抗感染能力方面的功效。在本研究中,从第1天到第7天,通过供水以每只鸡1×10 CFU的剂量给雏鸡施用[具体菌株名称]和商业益生菌,为雏鸡建立保护系统。在第8天和第9天,用[具体病原体名称]攻击雏鸡,以研究[具体菌株名称]与商业益生菌相比的预防效果和潜在机制。处理后,我们进行了广泛的测量,包括体重、免疫器官指数变化、肝脏、脾脏和盲肠中[具体菌株名称]的活菌计数以及肝脏的病理变化。我们的研究结果表明,[具体菌株名称]和商业益生菌都可以保护雏鸡免受[具体病原体名称]感染。数据还表明,益生菌用药可以减轻感染后的体重减轻,降低肝脏、脾脏和盲肠中的细菌数量,并减轻所有处理组雏鸡的肝脏病理损伤。随后,我们对感染后5天的雏鸡粪便微生物群进行了16S rRNA高通量测序。我们发现,[具体菌株名称]和商业益生菌都可以通过影响[具体菌属名称]、[具体菌属名称]和[具体菌属名称]的细菌种群来抵御[具体病原体名称]的入侵。一般来说,添加[具体菌株名称]作为饲料添加剂可保护黄羽肉鸡免受[具体疾病名称]侵害,表明其在 poultry industry 具有巨大的商业应用潜力。 (注:原文中部分关键信息缺失具体内容,已用[具体名称]表示)